Inelastic electron tunnelling induces anomalous light emission
Nature Nanotechnology, Published online: 17 May 2024; doi:10.1038/s41565-024-01664-8
A single monolayer semiconductor integrated into a plasmonic tunnel junction exhibits electroluminescence with photon energies that exceed the excitation electron potential. This phenomenon is shown to be indirectly triggered by inelastically tunnelling electrons.Single-molecule fluorescence multiplexing by multi-parameter spectroscopic detection of nanostructured FRET labels
Nature Nanotechnology, Published online: 15 May 2024; doi:10.1038/s41565-024-01672-8
FRETfluors—nanostructures with Cy3 and Cy5 dyes and a DNA scaffold—are used to generate distinct spectroscopic signals from different configurations and mixtures of mRNA, dsDNA and proteins in an anti-Brownian electrokinetic trap for single-molecule multiplexed sensing.Atomic-force-microscopy-based time-domain two-dimensional infrared nanospectroscopy
Nature Nanotechnology, Published online: 15 May 2024; doi:10.1038/s41565-024-01670-w
Integrating atomic force microscopy with time-domain two-dimensional infrared spectroscopy provides insights into molecular structures, mode coupling and energy transfers with high spatial resolution.Superionic fluoride gate dielectrics with low diffusion barrier for two-dimensional electronics
Nature Nanotechnology, Published online: 15 May 2024; doi:10.1038/s41565-024-01675-5
Superionic fluoride dielectrics with a low ion migration barrier are capable of excellent capacitive coupling and are highly compatible with scalable device manufacturing processes for integrated electronics.A large-scale machine learning analysis of inorganic nanoparticles in preclinical cancer research
Nature Nanotechnology, Published online: 15 May 2024; doi:10.1038/s41565-024-01673-7
This analysis leverages a large-scale literature review, text mining, statistics and machine learning to identify trends, shortcomings and future opportunities in developing and deploying inorganic nanoparticles for cancer diagnosis and therapy.Liposozyme for wound healing and inflammation resolution
Nature Nanotechnology, Published online: 13 May 2024; doi:10.1038/s41565-024-01656-8
Antibacterial action, along with restoration of redox and immune homeostasis, is achieved using a lipid–nanozyme hybrid for the healing of diabetic foot ulcers.Janus liposozyme for the modulation of redox and immune homeostasis in infected diabetic wounds
Nature Nanotechnology, Published online: 13 May 2024; doi:10.1038/s41565-024-01660-y
Therapies for treating bacterial infection and increasing wound healing are needed. Here the authors report a liposozyme that combines reactive oxygen species generation and scavenging for antibacterial action and modulation of redox and immune homeostasis, increasing wound healing.Nanoparticles for inducing Gaucher disease-like damage in cancer cells
Nature Nanotechnology, Published online: 13 May 2024; doi:10.1038/s41565-024-01668-4
Increased nutrient uptake of cancer cells offers a possible therapeutic target. Here, the authors designed a nanoparticle to deliver phenylboronic-acid-modified cholesterol which reacts in cancer cells to trigger Gaucher disease-like metabolic damage to tumour cells, demonstrating potential application.Single-site iron-anchored amyloid hydrogels as catalytic platforms for alcohol detoxification
Nature Nanotechnology, Published online: 13 May 2024; doi:10.1038/s41565-024-01657-7
Oral antidotes for consumption-related acute alcohol intoxication are needed. Here, the study presents amyloid fibrils of β-lactoglobulin, a milk-derived protein decorated by single-site iron, as a catalytic platform for alcohol detoxification in vivo and prophylactic protection against alcohol damage.Strain-resilient porous conductors with fewer nanofillers from in situ phase separation
Nature Nanotechnology, Published online: 10 May 2024; doi:10.1038/s41565-024-01661-x
Silver nanowires self-assembled on microscale elastomer pores, through in situ phase separation, yield highly elastic porous nanocomposite conductors with ultralow percolation threshold and high stretchability. This material is highly conductive, strain-insensitive and fatigue-tolerant, and holds promise for strain-resilient, wireless, battery-free bioelectronics.Redox-neutral electrochemical decontamination of hypersaline wastewater with high technology readiness level
Nature Nanotechnology, Published online: 09 May 2024; doi:10.1038/s41565-024-01669-3
A flow-through redox-neutral electrochemical reactor–electrodialysis system has been developed to recover water, alkali and acids from hypersaline wastewaters. This accelerates a shift in ‘zero-discharge’ technology from energy-intensive steam-driven to energy-efficient electrically driven processes.Gentler, nanoscale ion implantation
Nature Nanotechnology, Published online: 06 May 2024; doi:10.1038/s41565-024-01659-5
By manipulating the glass transition of the electrolyte, nanometre-resolution electrochemical ion implantation doping can be achieved in various polymeric semiconductors.Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses
Nature Nanotechnology, Published online: 06 May 2024; doi:10.1038/s41565-024-01655-9
The ability to vaccinate against multiple related pathogens is a significant advantage. Here, the authors report on quartets of linked receptor-binding domains attached to designed nanocages using SpyTag/SpyCatcher links, demonstrating effective vaccination against similar viruses as well as the variant of concern.Tuning light by the vibes
Nature Nanotechnology, Published online: 29 April 2024; doi:10.1038/s41565-024-01663-9
The emission wavelengths of semiconductor lasers based on group-IV materials can be efficiently reconfigured by using strained nanomechanical resonators.Actively tunable laser action in GeSn nanomechanical oscillators
Nature Nanotechnology, Published online: 29 April 2024; doi:10.1038/s41565-024-01662-w
An on-chip tunable laser operates by harnessing nanomechanical resonances at the radio frequency, achieving ultralow tuning power consumption.Phase-separated porous nanocomposite with ultralow percolation threshold for wireless bioelectronics
Nature Nanotechnology, Published online: 29 April 2024; doi:10.1038/s41565-024-01658-6
An in situ phase-separation method at microscale level creates stretchable superelastic porous nanocomposite conductors, reduces conductive filler usage and enables strain-resilient wireless wearable and implantable bioelectronics.Functionalized nanowires for miRNA-mediated therapeutic programming of naïve T cells
Nature Nanotechnology, Published online: 29 April 2024; doi:10.1038/s41565-024-01649-7
Ex vivo engineering of T cells for adoptive T-cell therapy without pre-activation is challenging and hinders therapeutic efficacy. Here, using nanowires, the delivery of microRNAs to primary naïve mouse and human CD8+ T cells without pre-activation for immune protection against pathogens is demonstrated.Toroidic phase transitions in a direct-kagome artificial spin ice
Nature Nanotechnology, Published online: 29 April 2024; doi:10.1038/s41565-024-01666-6
Toroidic phases and their phase transitions are notoriously hard to study in natural materials. Now, a direct-kagome spin ice provides access to two low-temperature toroidal phases, ferrotoroidicity and paratoroidicity, as well as to toroidic phase transitions.Self-assembly of peptide nanocapsules by a solvent concentration gradient
Nature Nanotechnology, Published online: 26 April 2024; doi:10.1038/s41565-024-01654-w
Biobased materials are of interest for many applications. Here the authors report insect-derived peptides that self-assemble into hollow nanocapsules through a gradient-driven, single-step, solvent exchange process, enabling the encapsulation of diverse cargoes with potential for drug delivery applications.Nanoscale doping of polymeric semiconductors with confined electrochemical ion implantation
Nature Nanotechnology, Published online: 22 April 2024; doi:10.1038/s41565-024-01653-x
A simple manipulation of an electrolyte’s glass transition enables nanoresolved electrochemical ion implantation doping in a variety of polymeric semiconductors.