Nature Nanotechnology provides a forum for the publication of top-quality research papers in all areas of nanoscience and nanotechnology. Coverage in Nature Nanotechnology extends from basic research in physics, chemistry and biology through to the development of new devices and technologies for applications in a wide range of industrial sectors. Organic, inorganic and hybrid materials are all covered.
Updated: 1 hour 35 min ago
Encoding molecular transport into DNA condensates
Nature Nanotechnology, Published online: 16 June 2025; doi:10.1038/s41565-025-01956-7
In the presence of complementary short oligonucleotide strands within synthetic DNA condensates, a striking mode of molecular transport is observed, revealing a sharp, wave-like diffusion front driven by phase-swelling effects and transitions in the material state of the condensates.
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Nanoneedles enable spatiotemporal lipidomics of living tissues
Nature Nanotechnology, Published online: 16 June 2025; doi:10.1038/s41565-025-01955-8
Arrays of silicon nanoneedles are used to generate molecular replicas of live brain tissue for longitudinal spatial lipidomic classification via desorption electrospray ionization mass spectrometry imaging of gliomas and to monitor the responses of the tumours to chemotherapy.
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A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapy
Nature Nanotechnology, Published online: 16 June 2025; doi:10.1038/s41565-025-01952-x
NICER is a broad-spectrum nanovaccine based on a nanovesicle system that can induce an effective immune response via epigenetic regulation to target both cancer stem-like cells and bulk tumour cells to prevent tumour recurrence.
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Electrically reconfigurable heteronuclear dual-atom catalysts
Nature Nanotechnology, Published online: 11 June 2025; doi:10.1038/s41565-025-01948-7
Scrutinizing the dynamic reconfiguration mechanism of intermetallic single-atom catalysts reveals the chemical origin of the enhanced electrocatalysis performance.
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Polymeric stabilization at the gas–liquid interface for durable solar hydrogen production from plastic waste
Nature Nanotechnology, Published online: 11 June 2025; doi:10.1038/s41565-025-01957-6
Polymeric stabilization of photocatalysts at the gas–liquid interface enhances both the catalytic activity and stability for solar hydrogen production from plastic waste. The photocatalyst retains its performance over 2 months under harsh conditions, and scaling to 1 m2 yields a hydrogen production rate of 0.906 l per day from polyethylene terephthalate waste under natural sunlight.
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Challenges and opportunities in DNA computing and data storage
Nature Nanotechnology, Published online: 10 June 2025; doi:10.1038/s41565-025-01937-w
Deoxyribonucleic acid (DNA) computing and data storage are emerging fields that are unlocking new possibilities in information technology. Here, we discuss technologies and challenges regarding using DNA molecules as computing substrates and data storage media.
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Atomic manipulation of the emergent quasi-2D superconductivity and pair density wave in a kagome metal
Nature Nanotechnology, Published online: 10 June 2025; doi:10.1038/s41565-025-01940-1
Scanning tunnelling microscopy experiments uncover a primary pair density wave at the reconstructed surface of the kagome metal CsV3Sb5, and tip-assisted, atomically precise manipulation of the reconstruction provides control over the emergent quasi-two-dimensional superconductivity.
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Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection
Nature Nanotechnology, Published online: 10 June 2025; doi:10.1038/s41565-025-01908-1
This work uses single-molecule techniques to show that conformational changes of the spike protein of SARS-CoV-2 modulate binding to its human receptor. The study provides key insights into the molecular mechanisms of virus infection and immune evasion.
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Scalable perovskite tandems enabled by dual-stage molecular regulation
Nature Nanotechnology, Published online: 09 June 2025; doi:10.1038/s41565-025-01946-9
A multifunctional additive enables facet-selective crystallization and defect passivation in wide-bandgap perovskites, unlocking scalable, efficient and stable all-perovskite tandem solar cells.
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Shuttling arrives for silicon quantum computers
Nature Nanotechnology, Published online: 09 June 2025; doi:10.1038/s41565-025-01942-z
Near-perfect shuttling of silicon spin qubits is demonstrated, closing a gap versus rival systems.
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High-fidelity single-spin shuttling in silicon
Nature Nanotechnology, Published online: 09 June 2025; doi:10.1038/s41565-025-01920-5
Conveyor-mode spin shuttling using a two-tone travelling-wave potential demonstrates an order of magnitude better spin coherence than bucket-brigade shuttling, achieving spin shuttling over 10 μm in under 200 ns with 99.5% fidelity in an isotopically purified Si/SiGe heterostructure.
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Ballistic diffusion fronts in biomolecular condensates
Nature Nanotechnology, Published online: 06 June 2025; doi:10.1038/s41565-025-01941-0
Adding short, complementary oligonucleotides to single-stranded DNA condensates creates a concentrated, linearly propagating, sharp diffusion front that contradicts the fuzzy concentration gradients and nonlinear kinetics typical of Fickian diffusion.
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Evolution of multivalent supramolecular assemblies of aptamers with target-defined spatial organization
Nature Nanotechnology, Published online: 06 June 2025; doi:10.1038/s41565-025-01939-8
Expanding aptamer binder space through tunable directed coevolution of supramolecular scaffolds helps discover nucleic-acid-based multivalent target binders capable of synergistic engagement that cannot be obtained through monovalent selection.
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Non-Hermitian non-Abelian topological transition in the <i>S</i> = 1 electron spin system of a nitrogen vacancy centre in diamond
Nature Nanotechnology, Published online: 06 June 2025; doi:10.1038/s41565-025-01913-4
By means of dilation methods and employing complex eigenvalue braids, non-Hermitian non-Abelian topological transitions are identified, which give rise to a third-order exceptional point.
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Ferroelastic writing of crystal directions in oxide thin films
Nature Nanotechnology, Published online: 05 June 2025; doi:10.1038/s41565-025-01950-z
Local shear stress from an atomic force microscope tip can control the crystal directions in thin oxide films. This approach enables the manipulation of local magnetic anisotropy in ferromagnetic metals.
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Mechanochemical carbon dioxide capture and conversion
Nature Nanotechnology, Published online: 05 June 2025; doi:10.1038/s41565-025-01949-6
Carbon dioxide can be efficiently captured and converted to methane under mild conditions by a mechanochemical approach that balances the thermodynamics and kinetics of CO2 methanation to simultaneously achieve high CO2 conversion and high CH4 selectivity.
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Interfacial reaction quantification enables long-cycling lithium metal batteries
Nature Nanotechnology, Published online: 04 June 2025; doi:10.1038/s41565-025-01938-9
A quantitative investigation of the interfacial reactions within lithium metal batteries (LMBs) reveals that the decomposition of lithium bis(fluorosulfonyl)imide leads to lithium-ion depletion and cell failure. Using these findings, an electrolyte was designed with an optimized salt concentration, ionic conductivity and dynamic viscosity, doubling the cycle life in a practical LMB.
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Unidirectional guided resonance continuum of Dirac bands in WS<sub>2</sub> bilayer metasurfaces
Nature Nanotechnology, Published online: 04 June 2025; doi:10.1038/s41565-025-01945-w
Unidirectional guided resonances can exist across nearly the entire band structure in glided WS2 bilayer metasurfaces.
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In vivo transformations of positively charged nanoparticles alter the formation and function of RuBisCO photosynthetic protein corona
Nature Nanotechnology, Published online: 03 June 2025; doi:10.1038/s41565-025-01944-x
Experimental and computational analyses indicated that positively charged nanoparticles experience pH- and lipid-coating-dependent transformations in plants that modify their impact on RuBisCO photosynthetic protein corona formation and function.
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Dynamic nanodomains dictate macroscopic properties in lead halide perovskites
Nature Nanotechnology, Published online: 02 June 2025; doi:10.1038/s41565-025-01917-0
Dynamic nanodomains in lead halide perovskites, dictated by A-site cations, crucially affect the optoelectronic properties by modulating electronic disorder and consequently enabling better solar cells and optoelectronic devices.
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