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NanoManufacturing

Michael De Volder, Engineering Department - IfM
 
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Table of Contents for Advanced Materials. List of articles from both the latest and EarlyView issues.
Updated: 1 hour 35 min ago

High‐Resolution Manifold Acoustic Holography Based on High‐Pixel‐Array Binary Metasurfaces

Mon, 24/03/2025 - 06:46

This work proposes an approach for the efficient generation of manifold acoustic holograms underwater by using high-pixel-array binary metasurfaces. Beyond generating simple-pattern holograms, it is shown that increasing the pixel numbers within a single metasurface allows for the creation of 2D/3D complex holographic fields. Moreover, it is demonstrated that holograms at multiple depths or frequencies can be encoded within one metasurface, thereby enhancing its information capacity. This work holds significant potential for applications in fields such as biomedical imaging and non-contact particle manipulation.


Abstract

Acoustic holograms using artificial materials have become an area of intense interest in acoustics due to the great potential in various applications such as medical imaging, underwater detection and object manipulation, etc. In this article, a general approach is proposed for designing high-pixel-array binary metasurfaces and then fabricating the intricate ultrathin structures via picosecond laser processing for implementing high-resolution manifold holograms in far fields. The angular spectrum propagation is utilized in combination with the forward optimization, instead of the Rayleigh-Sommerfeld integral, to efficiently simulate far-field holograms at the target plane. To obtain manifold acoustic holograms in the planes at different depths, zero-padding is utilized to break the tight constraint of sampling theorem. Benefiting from the realizable high-pixel-array binary metasurface, e.g., the number of pixels ≈90 000 or even more, high-resolution complicated holograms can be readily achieved. As an example, multi-depth holography, multi-frequency holography, and sophisticated holography are generated via binary metasurfaces. The functional meta-devices based on ultrasound amplitude modulations provide more opportunities for exploring practical applications of acoustic metamaterials.

Autonomous Bioelectronic Devices Based on Silk Fibroin

Mon, 24/03/2025 - 06:46

This review highlights the unique autonomous features of silk fibroin (SF), including self-healing, shape-morphing, and biodegradability, which enable its integration into bioelectronics. Key applications such as smart textiles, epidermal sensors, and adaptable implants are explored. The discussion addresses challenges in scalability, reproducibility, and bio-integration while presenting future directions for sustainable and multifunctional silk-based technologies.


Abstract

The development of autonomous bioelectronic devices capable of dynamically adapting to changing biological environments represents a significant advancement in healthcare and wearable technologies. Such systems draw inspiration from the precision, adaptability, and self-regulation of biological processes, requiring materials with intrinsic versatility and seamless bio-integration to ensure biocompatibility and functionality over time. Silk fibroin (SF) derived from Bombyx mori cocoons, has emerged as an ideal biomaterial with a unique combination of biocompatibility, mechanical flexibility, and tunable biodegradability. Adding autonomous features into SF, including self-healing, shape-morphing, and controllable degradation, enables dynamic interactions with living tissues while minimizing immune responses and mechanical mismatches. Additionally, structural tunability and environmental sustainability of SF further reinforce its potential as a platform for adaptive implants, epidermal electronics, and intelligent textiles. This review explores recent progress in understanding the structure–property relationships of SF, its modification strategies, and its great potential for integration into advanced autonomous bioelectronic systems while addressing challenges related to scalability, reproducibility, and multifunctionality. Future opportunities, such as AI-assisted material design, scalable fabrication techniques, and the incorporation of wireless and personalized technologies, are also discussed, positioning SF as a key material in bridging the gap between biological systems and artificial technologies.

Creating Vacancy Strong Interaction to Enable Homogeneous High‐Throughput Ion Transport for Efficient Solid‐State Lithium Batteries

Mon, 24/03/2025 - 06:45

Creating sulfur-vacancy-rich tungsten sulfide into composite polymer electrolyte enables homogeneous high-throughput Li-ion transport (ultra-high ionic conductivity of 1.9 × 10−3 S cm−1 at 25 °C) and uniform lithium deposition (ultra-long lifetime of over 5500 h in Li||Li cells). The sulfurized polyacrylonitrile||Li solid pouch cell exhibits an initial discharge-specific capacity of 1048 mAh g−1, resulting in a total capacity of 0.524 Ah.


Abstract

Solid polymer electrolytes are emerging as a key component for solid-state lithium metal batteries, offering a promising combination of large-scale processability and high safety. However, challenges remain, including limited ion transport and the unstable solid electrolyte interphase, which result in unsatisfactory ionic conductivity and uncontrollable lithium dendrite growth. To address these issues, a high-throughput Li-ion transport pathway is developed by incorporating tungsten sulfide enriched with sulfur vacancies (SVs) into a poly(vinylidene fluoride-co-hexafluoropropylene)-based composite polymer electrolytes (CPEs). The SVs strong interaction in the CPEs facilitates homogeneous high-throughput Li-ion transport 1.9 × 10−3 S cm−1 at 25 °C) by enhancing the dissociation of lithium salts and effectively creates ample interfaces with the polymer chains to reduce the formation of inner vacuities. Moreover, the SVs confine FSI− anions, while the electron-rich environment induced by sulfur atoms promotes the preferential degradation of bis(trifluoromethanesulfonyl)imide anions, ensuring uniform lithium deposition. This fosters the formation of inorganic nanocrystals on the lithium anode and effectively suppresses dendrite growth, enabling an ultra-long lifetime of over 5500 h in Li||Li symmetric cells. When paired with sulfurized polyacrylonitrile cathode, a pouch cell capacity of 0.524 Ah is achieved, demonstrating the effectiveness of a homogeneous, high-throughput Li-ions transport mechanism.

Engineering High‐Density Grain Boundaries in Ru0.8Ir0.2Ox Solid‐Solution Nanosheets for Efficient and Durable OER Electrocatalysis

Mon, 24/03/2025 - 06:45

Strategically engineered Ru0.8Ir0.2Ox ultrathin nanosheets with high-density grain boundaries exhibit enhanced oxygen evolution reaction performance in proton exchange membrane water electrolyzers. This design optimizes Ru-Ir interactions and charge distribution, reducing overpotential to 189 mV for 10 mA cm−2 and maintaining stability for >1000 h at industrial-scale current density. This advancement offers a pathway to efficient, cost-effective green hydrogen production.


Abstract

The oxygen evolution reaction (OER) in proton exchange membrane water electrolyzers (PEMWE) has long stood as a formidable challenge for green hydrogen sustainable production, hindered by sluggish kinetics, high overpotentials, and poor durability. Here, these barriers are transcended through a novel material design: strategic engineering of high-density grain boundaries within solid-solution Ru0.8Ir0.2Ox ultrathin nanosheets. These carefully tailored grain boundaries and synergistic Ir─Ru interactions, reduce the coordination of Ru atoms and optimize the distribution of charge, thereby enhancing both the catalytic activity and stability of the nanosheets, as verified by merely requiring an overpotential of 189 mV to achieve 10 mA cm−2 in acidic electrolyte. In situ electrochemical techniques, complemented by theoretical calculations, reveal that the OER follows an adsorption evolution mechanism, demonstrating the pivotal role of grain boundary engineering and electronic modulation in accelerating reaction kinetics. Most notably, the Ru0.8Ir0.2Ox exhibits outstanding industrial-scale performance in PEMWE, reaching 4.0 A cm−2 at 2 V and maintaining stability for >1000 h at 500 mA cm−2. This efficiency reduces hydrogen production costs to $0.88 kg−1. This work marks a transformative step forward in designing efficient, durable OER catalysts, offering a promising pathway toward hydrogen production technologies and advancing the global transition to sustainable energy.

Emergent Multiple Spin States From Baromagnetic Effect in Strongly Correlated Magnet Mn₃GaC

Mon, 24/03/2025 - 06:43

In kagome lattice magnet Mn₃GaC, controllable multiple spin states with giant baro-magnetoresistance effect, which can enhance magnetic storage, are achieved by manipulating spin rotation within the spin-polarized plane through applied pressure. These multiple spin states originate from the synergistic mechanism between spin frustration and spin polarization.


Abstract

Strongly correlated magnets, exhibiting distinctive spin properties such as spin-orbit coupling, spin polarization, and chiral spin, are regarded as the next-generation high-density magnetic storage materials in spintronics. Nevertheless, owing to intricate spin interactions, realizing controllable spin arrangement and high-density magnetic storage remains a formidable challenge. Here, controllable multiple spin states induced by the baromagnetic effect in kagome lattice magnet Mn₃GaC are first reported, achieved by manipulating spin rotation within the spin-polarized plane employing pressure. Neutron diffraction refinement and specific heat measurements under pressure, combined with first-principles calculations, demonstrate that multiple spin states are originating from the synergistic mechanism between spin frustration and spin polarization related to the lifting of degeneracy in electronic microstates. Electrical transport measurements under pressure reveal that multiple spin states exhibit giant baro-magnetoresistance effect, enabling enhanced storage density in spintronics via multi-logic state applications. Integrating the pressure response and microscopic behaviors of spins, a comprehensive p-T-H phase diagram is constructed, offering a novel and robust framework for multi-logic states. These findings provide critical insights into controllable spin states, opening a new avenue for high-density magnetic storage through multiple spin states.

Visible Periodic Piezoelectric Domains in Silk Fibroin for Neurite‐Orientated Extension

Mon, 24/03/2025 - 06:33

The piezoelectric SF film with visible periodic piezoelectric domains and excellent biocompatibility is fabricated through a feasible photochemical method with silver nanoparticles as the developer and mediator simultaneously. Consequently, the oriented piezoelectric electric field is achieved under ultrasound and effectively regulates the directional growth and length of neurite and neural gene expression.


Abstract

The development of visible periodic piezoelectric domains is highly attractive but challenging to overcome the homogeneous distribution and lack of visualization of the electric field on traditional piezopolymers. This work reports an in situ synthesis to create customized silver patterns with micron-level distinguishability. This method serves to form visible periodic piezoelectric domains and endows the silk fibroin (SF) piezoelectric generator with maximum root mean square current, energy density, and voltage of 5.1 mA, 6.7 W m−2 and 529.5 mV, respectively, under an ultrasound intensity of 1.0 W cm−2. The oriented piezoelectric electric field is periodically distributed into the SF film with ultrasound-driven assistance and remarkably regulates neurite directional growth, length, and gene expression. Additionally, these piezoelectric domains enable the direct and timely observation of the electric field's effect on neurites by biological microscopy. This approach paves the way for great potential in tailored electric stimulation for cell biology and medical engineering.

Dynamic GelMA/DNA Dual‐Network Hydrogels Promote Woven Bone Organoid Formation and Enhance Bone Regeneration

Mon, 24/03/2025 - 06:30

A dynamic, dual-network CGDE hydrogel, combining covalent and noncovalent crosslinking mimics the biochemical and mechanical cues of bone extracellular matrix. This viscoelastic matrix promotes 3D cellular self-organization and drives the development of functional woven bone organoids (WBOs) through intramembranous ossification, reaching peak bioactivity at 21 days. This approach offers a robust and scalable platform for bone organoid engineering.


Abstract

Bone organoids, in vitro models mimicking native bone structure and function, rely on 3D stem cell culture for self-organization, differentiation, ECM secretion, and biomineralization, ultimately forming mineralized collagen hierarchies. However, their development is often limited by the lack of suitable matrices with optimal mechanical properties for sustained cell growth and differentiation. To address this, a dynamic DNA/Gelatin methacryloyl (GelMA) hydrogel (CGDE) is developed to recapitulate key biochemical and mechanical features of the bone ECM, providing a supportive microenvironment for bone organoid formation. This dual-network hydrogel is engineered through hydrogen bonding between DNA and GelMA, combined with GelMA network crosslinking, resulting in appropriate mechanical strength and enhanced viscoelasticity. During a 21-day 3D culture, the CGDE hydrogel facilitates cellular migration and self-organization, promoting woven bone organoid (WBO) formation via intramembranous ossification. These WBOs exhibit spatiotemporal architectures supporting dynamic mineralization and tissue remodeling. In vivo studies demonstrate that CGDE-derived WBOs exhibit self-adaptive properties, enabling rapid osseointegration within 4 weeks. This work highlights the CGDE hydrogel as a robust and scalable platform for bone organoid development, offering new insights into bone biology and innovative strategies for bone tissue regeneration.

Grains > 2 µm with Regulating Grain Boundaries for Efficient Wide‐Bandgap Perovskite and All‐Perovskite Tandem Solar Cells

Mon, 24/03/2025 - 06:27

A simple and effective approach to grain boundary growth optimization: Incorporating a KTFB polyfluorinated additive into the antisolvent to regulate grain boundary growth, eliminate excessive halide lead and defects, and form wide-bandgap (1.78 eV) perovskite films with grain size over 2 µm, enabling the realization of efficient two-terminal and four-terminal all-perovskite tandem devices.


Abstract

Tandem perovskite solar cells represent a significant avenue for the future development of perovskite photovoltaics. Despite their promise, wide-bandgap perovskites, essential for constructing efficient tandem structures, have encountered formidable challenges. Notably, the high bromine content (>40%) in these 1.78 eV bandgap perovskites triggers rapid crystallization, complicating the control of grain boundary growth and leading to films with smaller grain sizes and higher defect density than those with narrower bandgaps. To address this, potassium tetrakis(pentafluorophenyl)borate molecules are incorporated into the antisolvent, employing a crystallographic orientation-tailored strategy to optimize grain boundary growth, thereby achieving wide-bandgap perovskite films with grains exceeding 2 µm and effectively eliminating surplus lead halide and defects at the grain boundaries. As a result, remarkable efficiency is achieved in single-junction wide-bandgap perovskite devices, with a power conversion efficiency (PCE) of 20.7%, and in all-perovskite tandem devices, with a two-terminal PCE of 28.3% and a four-terminal PCE of 29.1%, which all rank among the highest reported values in the literature. Moreover, the stability of these devices has been markedly improved. These findings offer a novel perspective for driving further advancements in the perovskite solar cell domain.

Hetero‐Trimetallic Atom Catalysts Enable Targeted ROS Generation and Redox Signaling for Intensive Apoptosis and Ferroptosis

Mon, 24/03/2025 - 06:26

A typical paradigm to utilize hetero-trimetallic atom catalysts (CCF TACs@NVs) with a stable symmetrical pyramid structure for catalytic guided apoptosis and ferroptosis-induced cell death, which is provided by the multi-enzymes like abilities under effective tumor aggregation, highlighting the application prospects in the biomedical field.


Abstract

Reactive oxygen species (ROS) play crucial roles in cellular metabolic processes by acting as primary intracellular chemical substrates and secondary messengers for cellular signal modulation. However, the artificial engineering of nanozymes to generate ROS is restricted by their low catalytic efficiency, high toxicity, and off-target consumption. Herein, hetero-trimetallic atom catalysts (TACs) anchored on a stable symmetrical pyramid structure are designed in the presence of N and P surface ligands from cross-linked polyphosphazene interlayer-coated MIL-101(Fe). The 3D network TACs with a uniform dispersion of Cu, Co, and Fe hetero-single atoms effectively tailor the active sites to avoid metal sintering, thereby providing sufficient catalytic activity for ROS blooms. Nanovesicle membranes facilitate the stable accumulation of nanozymes with homologous targeting, recognition, and endocytosis, effectively addressing the potentially high toxicity and off-target defects. Therefore, the outcome of the in situ ROS-bloom acts as a redox signal for directly regulating oxidative stress in the tumor microenvironment. Meanwhile, ROS intervene in the glutathione peroxidase 4, long-chain acyl-CoA synthetase 4, and cysteinyl aspartate specific proteinase-3 pathways as second messengers, fostering the proclivity toward apoptosis and lipid peroxidation-regulated ferroptosis pathway concurrently, thereby highlighting the application prospects of TACs in the biomedical field.

Suspension Electrolytes with Catalytically Self‐Expediating Desolvation Kinetics for Low‐Temperature Zinc Metal Batteries

Mon, 24/03/2025 - 06:25

The CeO2- x -suspension electrolyte is initially proposed to regulate the Zn[(H2O)6]2+ solvation structure and alters the inner Helmholtz plane to accelerate Zn[(H2O)6]2+ desolvation, achieving a homogenized electric field and uniform ion flux kinetics. Consequently, the suspen sion electrolyte achieves a service life exceeding 6500 h at 0 °C and demonstrates outstanding rate performance at −20 °C, highlighting its practical potential for AZMBs.


Abstract

The conventional electrolyte for rechargeable aqueous zinc metal batteries (AZMBs) breeds many problems such as Zn dendrite growth and side reaction of hydrogen evolution reaction, which are fundamentally attributed to the uneven ion flux owing to the high barriers of desolvation and diffusion of Zn[(H2O)6]2+ clusters. Herein, to modulate the [Zn(H2O)6]2+ solvation structure, the suspension electrolyte engineering employed with electron-delocalized catalytic nanoparticles is initially proposed to expedite desolvation kinetics. As a proof, the electron-density-adjustable CeO2- x is introduced into the commercial electrolyte and preferentially adsorbed on the Zn surface, regulating the Zn[(H2O)6]2+ structure. Meanwhile, the defect-rich CeO2- x redistributes the localized space electric field to uniformize ion flux kinetics and inhibits dendrite growth, as confirmed by a series of theoretical simulations, spectroscopical and experimental measurements. Encouragingly, the CeO2- x decorated suspension electrolyte enables a long stability over 1200 cycles at 5 mA cm−2 and an extended lifespan exceeding 6500 h with lower overpotentials of 34 mV under 0 °C. Matched with polyaniline cathodes, the full cells with suspension electrolyte exhibit a capacity-retention of 96.75% at 1 A g−1 under −20 °C as well as a long lifespan of up to 400 cycles in a large-areal pouch cell, showcasing promising potentials of suspension electrolyte for practical AZMBs.

Eye‐Drop Nano‐Formulation of Catalase Self‐Assembled with Thiolated Chitosan for Effective Treatment of Dry Eye Disease

Mon, 24/03/2025 - 06:25

An eye-drop nano-formulation of catalase self-assembled with cysteine-modified chitosan is designed. The obtained nanoparticles after eye-drop administration could form disulfide bonds with the mucin layer of the team film to achieve enhanced precorneal adhesion, so as to continuously eliminate excessive reactive oxygen species accumulated in the ocular surface to suppress inflammation, resulting in effective treatment of dry eye disease.


Abstract

Dry eye disease (DED), the most prevalent ophthalmological condition worldwide, can cause severe ocular discomfort and even visual impairment. Effective yet safe therapeutics for severe DED are still highly demanded. Herein, considering the important role of excessive reactive oxygen species (ROS) in triggering DED, an eye-drop nano-formulation of catalase (CAT) self-assembled with cysteine-modified chitosan (CS-Cys) is designed for DED treatment. Upon eye-drop administration of CS-Cys/CAT nanoparticles, CS-Cys can form disulfide bonds with abundant thiols in the mucin layer of the tear film, anchoring catalase to the corneal surface. Thus the excess ROS accumulated on the ocular surface can be effectively eliminated, resulting in a regulated tear microenvironment. In mouse and rabbit models, it is verified that CS-Cys/CAT eye drops can offer excellent therapeutic effects, especially in promoting the recovery of damaged epithelium and increasing tear secretion. Remarkably, CS-Cys/CAT eye drops showed notably better therapeutic performance than clinically used cyclosporin and dexamethasone, as well as several new DED drugs in clinical trials. Thus, the work presents a unique nanoparticulate eye-drop-based ocular delivery system to allow prolonged ocular retention of protein therapeutics, and such nanoformulation formulated by fully biocompatible/biodegradable components possesses significant translational potential for effective and safe DED treatment.

Improved Facet and Edge Passivation in Near‐Infrared III‐V Colloidal Quantum Dot Photodetectors

Mon, 24/03/2025 - 06:21

Increasing InAs CQD size exposes diverse facets and edges, bringing challenges for effective passivation. This work introduces a mixed-halide passivation strategy to stabilize these facets and edges, doubling anti-oxidation ability and boosting mobility. The resulting photodetectors achieve 75% EQE, 10 ns response time, and 50 h operational stability (10% loss) at 1140 nm, advancing InAs CQD photodetector performance.


Abstract

Lead-free III-V colloidal quantum dots (CQDs) are of significant interest for their potential in near-infrared (NIR) to short-wave infrared (SWIR) photodetection. However, achieving effective surface passivation remains challenging, especially as larger CQD sizes introduce more complex surface facets and compositions while shifting the absorption peak from the NIR to the SWIR range. In this study, a mixed-halide passivation strategy is developed for large InAs CQDs, an approach that led to a doubling in anti-oxidation ability and achieves a hole mobility of 0.03 cm2 Vs−1. These in turn led to a T90 lifetime of 50 h and enhanced operating stability in photodetectors operating at 1140 nm. Density functional theory (DFT) simulations and facet characterization indicate that exposed facets and edges are well passivated using a mixture of indium halides, which provide a stronger desorption energy compared to single-halide passivation. This approach yields photodetectors with an external quantum efficiency (EQE) of 75% and a response time of 10 ns, an advance for InAs photodetectors operating at 1140 nm.

Ir/Mn Co‐Mixing and Oxide‐Support Interaction Modulation Through Plasma Promoted Asymmetric Oxygen Coupling for Stable Acidic Oxygen Evolution

Mon, 24/03/2025 - 06:20

A strategy that integrates the Ir/Mn co-mixing and the strong oxide-support interaction modulation through plasma defect engineering is used for the development of the catalysts that follow the oxide path mechanism for the oxygen-evolution reaction (OER). The obtained catalyst shows exceptional OER activity and remarkable stability in the acid media.


Abstract

Developing efficient and stable catalysts that facilitate the oxygen-evolution reaction (OER) through an oxide-path mechanism (OPM) is of considerable interest. However, it remains a significant challenge due to the stringent structural requirements of these catalysts. This work reports that using a strategy that integrates the Ir/Mn co-mixing and the strong oxide-support interaction (SOSI) modulation, efficient and stable Ir-based catalysts that follow the OPM for the acidic OER can be developed. The strategy mainly relies on optimizing the distance of oxygeneous intermediate adsorption sites by the Ir/Mn co-mixing and modulating the SOSI of the catalysts through plasma defect engineering to trigger the OPM pathway with a lower energy barrier. The density-functional-theory (DFT) calculations reveal a strong electronic coupling between Ir and Mn via the Ir─O─Mn bond and a ready coupling of oxygeneous adsorbed on the Ir site with those on the Mn site, leading to an asymmetric oxygen coupling for the OER. The developed catalyst merely requires an overpotential of 240 mV to drive 10 mA cm−2 with the Ir mass-activity > 75 times higher than that of the IrO2. When used in the proton-exchange-membrane water-electrolyzers, it shows high performance and excellent stability at an industrial-level current density of 1.0 A cm−2.

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