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Michael De Volder, Engineering Department - IfM
 
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This is a superlist of research seminars in Cambridge open to all interested researchers. Weekly extracts of this list (plus additional talks not yet on talks.cam) are emailed to a distribution list of over 200 Cambridge researchers by Research Services Division. To join the list click here https://lists.cam.ac.uk/mailman/listinfo/biophy-cure For more information see http://www.cure.group.cam.ac.uk or email drs45[at]rsd.cam.ac.uk
Updated: 1 day 9 hours ago

Tue 30 Sep 11:45: Cambridge MedAI Seminar - September 2025

Tue, 23/09/2025 - 12:34
Cambridge MedAI Seminar - September 2025

Sign up on Eventbrite: https://medai_september2025.eventbrite.co.uk

Join us for the Cambridge AI in Medicine Seminar Series, hosted by the Cancer Research UK Cambridge Centre and the Department of Radiology at Addenbrooke’s. This series brings together leading experts to explore cutting-edge AI applications in healthcare—from disease diagnosis to drug discovery. It’s a unique opportunity for researchers, practitioners, and students to stay at the forefront of AI innovations and engage in discussions shaping the future of AI in healthcare.

This month’s seminar will be held on Tuesday 30 September 2025, 12-1pm at the Jeffrey Cheah Biomedical Centre (Main Lecture Theatre), University of Cambridge and streamed online via Zoom. A light lunch from Aromi will be served from 11:45. The event will feature the following talks:

Automated Lesion Segmentation of Stroke MRI Using nnU-Net: A Comprehensive External Validation – Dr Tammar Truzman, Postdoctoral Fellow, MRC Cognition and Brain Sciences Unit, University of Cambridge

Dr Tammar Truzman is a Postdoctoral Fellow at the MRC Cognition and Brain Sciences Unit, University of Cambridge, working with Prof. Matt Lambon Ralph and Dr. Ajay Halai. Her research focuses on language assessment and recovery in people with aphasia, combining neuroimaging, language rehabilitation, and computational modeling. She is also a licensed speech-language pathologist with expertise in language therapy and clinical translation.

Abstract: Accurate lesion segmentation is a critical step in stroke neuroimaging, both for advancing theoretical understanding of brain–behavior relationships and for enabling clinical applications. Deep learning methods have recently shown promise, but external validation across diverse datasets remains limited. In this talk, I will present a comprehensive evaluation of nnU-Net for stroke lesion segmentation across multiple acute and chronic datasets. I will discuss factors influencing model performance and generalization, including imaging modality, dataset size and quality and lesion volume. The results highlight both the potential and the current limitations of automated segmentation tools for translational use in stroke and aphasia research.

Deep Learning-Based Follicle Growth Prediction using a Transformer Architecture – Artsiom Hramyka, Postdoctoral Fellow, University of Cambridge

Artsiom is a Postdoctoral Researcher in Computer Science and Medicine at the University of Cambridge, where his work involves applying artificial intelligence and simulation modelling to solve complex healthcare problems. This research builds upon his doctoral work at the University of St Andrews, where he is completing his PhD thesis on the application of novel analytical frameworks and AI in healthcare. Currently, his primary focus is on the early detection of cancer as part of the CRUK International Alliance for Cancer Early Detection (ACED). In this role, he develops and calibrates multistate models that simulate the natural history of malignant cancers to evaluate and optimise screening strategies. His research also extends to other areas of medicine, including active collaborations where he applies machine learning to enhance fertility treatments with Imperial College London and to analyse treatment data in paediatric oncology with the Charlotte Maxeke Johannesburg Academic Hospital.

Abstract: Traditional methods for predicting ovarian follicle growth rely on the clinically unfeasible assumption of tracking individual follicles between ultrasound scans. This research introduces a novel approach that overcomes this limitation by predicting the entire follicle size distribution. We developed a decoder-only, GPT -like Transformer architecture to autoregressively forecast future follicle profiles from sequential scan data. Model performance was evaluated using distribution-level metrics, including Earth Mover’s Distance (EMD) and Chi-Square distance, across three clinically relevant scenarios simulating different data availability. Systematic hyperparameter optimisation resulted in a performance increase, a 10.2% improvement in EMD for short-term predictions. A key finding is the robust performance of the model when using only a single initial scan, demonstrating its potential utility in cases with missed appointments and highlighting the importance of training-inference consistency. This work represents the first application of a Transformer architecture for distribution-level follicle prediction, offering a more realistic tool for clinical decision support in assisted reproductive technology.

This is a hybrid event so you can also join via Zoom:

https://zoom.us/j/99050467573?pwd=UE5OdFdTSFdZeUtIcU1DbXpmdlNGZz09

Meeting ID: 990 5046 7573 and Passcode: 617729

We look forward to your participation! If you are interested in getting involved and presenting your work, please email Ines Machado at im549@cam.ac.uk

For more information about this seminar series, see: https://www.integratedcancermedicine.org/research/cambridge-medai-seminar-series/

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Fri 23 Jan 16:00: Title to be confirmed

Tue, 23/09/2025 - 12:07
Title to be confirmed

Abstract not available

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Fri 28 Nov 16:00: Title to be confirmed

Tue, 23/09/2025 - 12:04
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Abstract not available

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Fri 21 Nov 16:00: Title to be confirmed

Tue, 23/09/2025 - 12:02
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Fri 14 Nov 16:00: Title to be confirmed

Tue, 23/09/2025 - 12:01
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Abstract not available

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Fri 31 Oct 16:00: Title to be confirmed

Tue, 23/09/2025 - 12:01
Title to be confirmed

Abstract not available

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Fri 17 Oct 16:00: Introduction to the DVRG and poster session

Tue, 23/09/2025 - 12:00
Introduction to the DVRG and poster session

Abstract not available

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Fri 28 Nov 14:00: Mechanics and data science to model aneurysms

Tue, 23/09/2025 - 11:53
Mechanics and data science to model aneurysms

Abstract not available

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Wed 19 Nov 16:00: Title to be confirmed

Tue, 23/09/2025 - 10:27
Title to be confirmed

Abstract not available

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Thu 02 Oct 11:30: Fracture Network Connectivity and Its Evolution

Tue, 23/09/2025 - 09:55
Fracture Network Connectivity and Its Evolution

Fractures are ubiquitous in crustal rocks due to the harsh environment of the deep subsurface and the inherent brittleness of the rock. These fractures, which represent planes of rock failure, significantly influence rock stability and are pivotal in predicting geohazards. Additionally, fractures typically provide highly permeable pathways for fluid flow in the subsurface, making them crucial for oil and gas exploration and production, subsurface hydrogen storage, geological CO₂ sequestration, and nuclear waste disposal.

Connectivity is a key characteristic of fracture networks, intricately linked to their mechanical and hydrological properties. In this seminar, an automated fracture interpretation technique is introduced, enabling the acquisition of large amounts of natural fracture data. Subsequently, an efficient discrete fracture network modeling software is presented, allowing the generation of complex fracture networks and the realization of advanced functionalities. Novel fracture metrics for single and multiple fracture clusters are also introduced, providing a means to quantify the connectivity of complex fracture networks and investigate potential influential factors. A DEM -LBM method is adopted to simulate the hydraulic fracturing process, demonstrating the dynamic evolution of fracture networks under significant stress disturbances. During this process, the dynamic evolution of connectivity can be characterized using the proposed novel metrics.

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Thu 06 Nov 15:00: Title to be confirmed

Tue, 23/09/2025 - 08:28
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Abstract not available

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Tue 27 Jan 16:00: Title to be confirmed

Tue, 23/09/2025 - 08:24
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Thu 25 Sep 14:00: The Many Guises of Reactive Metabolite Signalling

Mon, 22/09/2025 - 16:22
The Many Guises of Reactive Metabolite Signalling

We present how a combination of small-molecule chemistry, chemical biology, and model-organism engineering biology helps to resolve the key mechanistic puzzles surrounding reactive metabolite signalling in health & disease. Focus will be placed on innovations and applications of interdisciplinary technologies with which we can decode the multifaceted biology of reactive metabolites in living systems with precise timing, locale, contexts, and metabolite-chemotype, and how the resulting new knowledge illuminates streamlined therapeutic avenues. Speaker bio: Aye completed her undergraduate studies in chemistry at Oxford UK (2000-2004), and doctoral research in organic chemistry with Prof. David Evans at Harvard University (2004-2009). She then switched her research discipline to life science and received her postdoctoral training with Prof. JoAnne Stubbe at MIT (2009-2012). Science in the Aye lab seeks to understand non-canonical cell signalling processes. Her laboratory is most well-known for investigations into electrophile signalling, a nuanced communication mode whereby on-target engagement between specific reactive metabolites and target proteins, orchestrates precision responses at cellular/organismal levels.

Contributions from her team have been recognised by several honours; recent examples include: 2025 ERC Advanced Grant, 2024 UK Academy of Medical Sciences Professorship, Klaus Grohe Prize in Drug Discovery, 2022 ERC Consolidator Grant, 2021 Tetrahedron young investigator award, International Chemical Biology Society Global Lectureship Award for distinguished investigators in chemical biology, ACS Arthur Cope Scholar, and 2020 ACS Eli Lilly award in biological chemistry.

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Wed 22 Oct 16:00: Title to be confirmed

Mon, 22/09/2025 - 11:10
Title to be confirmed

Abstract not available

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Thu 30 Oct 11:30: Title to be confirmed

Mon, 22/09/2025 - 10:32
Title to be confirmed

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Thu 02 Oct 15:30: Chronic stress-mediated effects on the immune system: links to mental health Note unusual time

Mon, 22/09/2025 - 09:59
Chronic stress-mediated effects on the immune system: links to mental health

Dr. Stacey Kigar is a research associate in the Department of Medicine and affiliate of the Department of Psychiatry at Cambridge. She obtained her PhD in Molecular and Cellular Pharmacology at the University of Wisconsin-Madison, and did postdoctoral work at the National Institute of Mental Health in the United States before moving to Cambridge in September 2020. Dr. Kigar uses both preclinical animal models and clinical research samples to investigate biological mechanisms underlying mental health and neurological disorders. She is generously supported by the Cambridge BRC , Alzheimer’s Research UK, and the MindEd Charitable Trust.

Hosting: Dr Chrysa Kapeni, CRUK

Note unusual time

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Wed 01 Oct 18:45: A Buzzing of Bees: Tales of Honeybees Through History Joint meeting with the Cambridgeshire Beekeepers' Association (NB Wednesday)

Sun, 21/09/2025 - 13:02
A Buzzing of Bees: Tales of Honeybees Through History

Dino Martins will talk about the relationship between honeybees and people.

Honeybees are one of the most familiar and widespread insects that are kept, managed, exploited and familiar to humanity. It is often said that ‘There is a crisis around bees’, but the reality is that overall honeybee numbers are actually increasing worldwide, the result of more intensive management, mass production and commercial trade of queens and colonies.

With examples drawn from around the world, this talk will highlight the complex, multi-faceted relationship we have with honeybees and explore how we can all play a role in better stewardship of the planet.

Joint meeting with the Cambridgeshire Beekeepers' Association (NB Wednesday)

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Thu 09 Oct 18:45: The Past and Future of Natural History

Sun, 21/09/2025 - 13:02
The Past and Future of Natural History

Brian Eversham will present a history of naturalists over 3000 years, of trends in wildlife and the study of wildlife, and some personal thoughts on where it’s heading, and where the next generation of field naturalists might come from.

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