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NanoManufacturing

Michael De Volder, Engineering Department - IfM
 

Wed 14 May 11:15: Title to be confirmed

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:54
Title to be confirmed

Abstract not available

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Wed 19 Mar 11:15: Title to be confirmed

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:53
Title to be confirmed

Abstract not available

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Wed 05 Mar 11:15: Emergent phenomena in nanosculpted devices of quantum materials

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:52
Emergent phenomena in nanosculpted devices of quantum materials

Electrons typically traverse a conductive medium in a diffusive manner, resulting in a linear relationship between the measured voltage and applied current – known as Ohm’s law. However, violations of Ohm’s law may be found when the inherent symmetries of the underlying system are broken. Examples include the sliding motion of density waves; ballistic or hydrodynamic electron transport; or the symmetry-breaking realised by lattice or magnetic order. Focused ion beam (FIB) fabrication methods enable precise nanoscale devices to be fashioned from high-quality single crystalline materials, ideal for exploring these nonlinear phenomena. Such nanoengineering offers vast potential for the investigation of both fundamental physics and the development novel quantum devices. In this talk, I will introduce three specific examples. Firstly, we will explore the current-induced sliding motion of a skyrmion lattice in Gd2PdSi3 and the resulting emergent electrodynamics, which originate from a time-dependent Berry phase. Secondly, I will highlight our latest breakthrough to develop FIB fabrication of three dimensional nanostructures, in the form of helical-shaped devices of the high-mobility Weyl magnet CoSn2S2. By breaking inversion symmetry on the length scale of the electron mean free path, we observe large nonreciprocal transport, resulting in a switchable diode effect. Finally, if time permits, I will discuss the possibility to fabricate highly symmetrical devices, which allows the probing of symmetry breaking along multiple directions of a material simultaneously – in this case exploited to study signatures of p-wave magnetism in Gd3Ru4Al12.

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Thu 27 Mar 09:30: Revealing the Unseen: AI's Role in Novel Target Discovery for High Unmet Needs Areas Through Multi-Omics Integrationce for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:50
Revealing the Unseen: AI's Role in Novel Target Discovery for High Unmet Needs Areas Through Multi-Omics Integrationce for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities

The role of AI and data-driven methodologies is set to play a huge part in the drug discovery industry, allowing intricate details of a multitude of disease mechanisms and improving the way for the streamlined development of therapeutics. The focus of this seminar would give an overview of how AI and Multi-Omics are shaping betterment in the area of the improved identification and profiling of therapeutic targets.

I will describe the general AI principles and show how they apply to drug discovery in a manner that can be followed by a wide audience. This should give the participants with even the barest understanding of the technical background an understanding of the value that this tool adds in drug discovery. I shall take our research using AI and machine learning coupled with advanced mathematical models. Integrative analysis of multi-omics datasets enabled identifying new targets and pathways that may suggest new avenues for their use in understanding complex biological questions.

The presentation also focuses on how such academic insights work out in the domain of commerce and further reflected through my experiences of founding and running AI-driven Startups: Kure.ai Therapeutics and CardiaTec Biosciences. The second one will bring out examples that evidently show the relevance of our findings in practical scenarios of developing innovative solutions in the area of cardiovascular diseases.

The talk concludes with a Q&A session and gives a very succinct but also very full picture of the role of AI and data-driven methods in modern drug discovery. It is in this regard that the subject of the seminar will put forth how these emerging technologies are enablers for increased precision and efficiency in the development of therapeutics today or will be, thus allowing an informed discussion among participants hailing from academia to biotech to big pharmaceuticals.

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Expanding the Temperature Range for Stable Aqueous Batteries: Strategies, Mechanisms and Perspectives

http://feeds.rsc.org/rss/ee - Tue, 04/02/2025 - 10:44
Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D4EE05304D, Review ArticleXianwei Fu, Ruijuan Shi, Ye Liu, Xiaoxiao He, Qian Li, Yan Zhang, Yong Zhao, Shilong Jiao
Aqueous batteries (ABs) based on water-containing electrolytes are intrinsically safe and serve as promising candidates for the grid-scale energy storage and power supplies of wearable electronics. The severe temperature fluctuations...
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Scalable Copper Current Collectors with Precisely Engineered Lithiophilic Alloy “Skins” for Durable Lithium-Metal Batteries

http://feeds.rsc.org/rss/ee - Tue, 04/02/2025 - 10:44
Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D4EE05862C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Huiqun Wang, Yuxiang Mao, Peng Xu, Yu Ding, Huiping Yang, Jian-Feng Li, Yu Gu, Jiajia Han, Li Zhang, Bingwei Mao
Depositing a uniform lithium metal layer on a highly conductive current collector (CC) is essential for the development of next-generation Li metal batteries (LMBs). However, poor cycling stability, low Coulombic...
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Sodium cluster-driven safety concerns of sodium-ion batteries

http://feeds.rsc.org/rss/ee - Tue, 04/02/2025 - 10:44

Energy Environ. Sci., 2025, Advance Article
DOI: 10.1039/D4EE05509H, PaperJiaping Niu, Junyuan Dong, Xiaohu Zhang, Lang Huang, Guoli Lu, Xiaolei Han, Jinzhi Wang, Tianyu Gong, Zheng Chen, Jingwen Zhao, Guanglei Cui
This study reveals that quasi-metallic sodium clusters in hard carbon possess an electron state density even higher than that of metallic sodium, making them more susceptible to triggering thermal runaway compared to lithium in graphite.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Repairing the interfacial defect via preferable adsorption of ytterbium enables high-utilization and dendrite-free Zn metal anode

http://feeds.rsc.org/rss/ee - Tue, 04/02/2025 - 10:44
Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D4EE05382F, PaperLong Jiang, Zhenyue Xing, Yanfen Liu, Xiaodong Shi, Le Li, Yangyang Liu, Bingan Lu, Jiang Zhou
Dendrite growth and spontaneous corrosion of zinc (Zn) metal anodes pose significant challenges for their application in grid-scale energy storage, primarily due to the instability of the bulk phase characterized...
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A Highly Efficient Electrolysis System Enabled by Direct Impedance Matching Between Charge Migration Triboelectric Nanogenerator and Series Connected Electrolysers

http://feeds.rsc.org/rss/ee - Tue, 04/02/2025 - 10:44
Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D4EE05522E, PaperYu Deng, Qian Qin, Wencong He, Hengyu Guo, Jie Chen
As an electromechanical conversion technology, triboelectric nanogenerators (TENGs) are widely used in water electrolysis for hydrogen production. Nevertheless, the impedance mismatch between TENGs and conventional electrolysers significantly reduces energy utilization...
The content of this RSS Feed (c) The Royal Society of Chemistry

Tue 04 Mar 14:00: Towards a Faster Finality Protocol for Ethereum - RESCHEDULED

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:09
Towards a Faster Finality Protocol for Ethereum - RESCHEDULED

Ethereum’s Gasper consensus protocol typically requires 64 to 95 slots—the units of time during which a new chain extending the previous one by one block is proposed and voted—to finalize, even under ideal conditions with synchrony and honest validators. This exposes a significant portion of the blockchain to potential reorganizations during changes in network conditions, such as periods of asynchrony.

In this talk, I will introduce 3SF, a novel consensus protocol that addresses these limitations. With 3SF, finality is achieved within just three slots after a proposal, drastically reducing the exposure to reorganizations. This presentation will explore the motivation, design, and implications of 3SF, offering a new perspective on the future of Ethereum’s consensus protocol.

Paper: https://arxiv.org/abs/2411.00558

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Thu 13 Feb 14:00: Embryo-scale reverse genetics at single cell resolution reveals lineage-specific modules underlying cranial development Host - Ben Steventon

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:08
Embryo-scale reverse genetics at single cell resolution reveals lineage-specific modules underlying cranial development

The Saunders lab is interested in understanding the interplay between a cell’s developmental history, function, and its flexibility to change. We use zebrafish as a model system to explore the limits of cell fate specification. By combining scalable single cell RNA -sequencing methods, lineage tracing, and genetic tools, we aim to study these complex developmental processes at multiple scales (molecular, cellular, organismal). We leverage single-animal barcoding strategies to enable quantification of molecular and cellular phenotypes in whole developing embryos, with the ultimate goal of understanding how animals overcome genetic and environmental perturbations and how this underlies morphological evolution.

Host - Ben Steventon

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Tue 04 Feb 14:00: Researchers‘ experiences with vulnerability disclosures

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:03
Researchers‘ experiences with vulnerability disclosures

Vulnerabilities are becoming more and more prevalent in scientific research. Researchers usually wish to publish their research and, before that, have the vulnerabilities acknowledged and fixed, contributing to a secure digital world. However, the vulnerability disclosure process is fraught with obstacles, and handling vulnerabilities is challenging as it involves several parties (vendors, companies, customers, and community). We want to shed light on the vulnerability disclosure process and develop guidelines and best practices, serving vulnerability researchers as well as the affected parties for better collaboration in disclosing and fixing vulnerabilities.

We collected more than 1900 research papers published at major scientific security conferences and analyzed how disclosures are reported, finding inconsistent reporting, as well as spotty acknowledgments and fixes by affected parties. We then conducted semi-structured interviews with 21 security researchers with a broad range of expertise who published their work at scientific security conferences and qualitatively analyzed the interviews.

We discovered that the main problem starts with even finding the proper contact to disclose. Bug bounty programs or general-purpose contact email addresses, often staffed by AI or untrained personnel, posed obstacles to timely and effective reporting of vulnerabilities.

Experiences with CERT (entities supposed to help notify affected parties and facilitate coordinated fixing of vulnerabilities) were inconsistent, some extremely positive, some disappointing. Our interviewees further talked about lawsuits and public accusations from the vendors, developers, colleagues, or even the research community. Successful disclosures often hinge on researcher experience and personal contacts, which poses personal and professional risks to newer researchers.

We’re working on making our collected best practices and common pitfalls more widely known both to researchers and industry, for more cooperative disclosure experiences.

Bio: Yasemin Acar (she/her) is a professor of computer science at Paderborn University, Germany, and a research assistant professor at The George Washington University. She focuses on human factors in computer security. Her research centers humans, their comprehension, behaviors, wishes and needs. She aims to better understand how software can enhance users’ lives without putting their data at risk. Her recent focus has been on human factors in secure development, investigating how to help software developers implement secure software development practices. Her research has shown that working with developers on these issues can resolve problems before they ever affect end users. Her research has won distinguished paper awards at IEEE Security and Privacy and USENIX Security, as well as a NSA best cyber security paper competition. Her web page: https://yaseminacar.de.

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Fri 14 Feb 14:00:  Anomalous fluctuations in stochastic cellular automata

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 10:00
 Anomalous fluctuations in stochastic cellular automata

Anomalous fluctuations are phenomena where hydrodynamic fluctuations in the system behave in a way that violates usual expectations, e.g. typical fluctuations that are Gaussian. It was discovered recently that certain many-body systems exhibit such fluctuations, and one of the most notable examples is the isotropic spin-1/2 Heisenberg chain whose spin transport shows a surprising “partial” Kardar-Parisi-Zhang (KPZ) physics. Such partial KPZ behaviour has been also experimentally confirmed using superconducting qubits, where it was observed that the higher spin cumulants behave in a way that is not controlled by any known KPZ sub universality class (e.g. GUE or Baik-Rains). In this talk, I will introduce a hydrodynamic framework based the ballistic macroscopic fluctuation theory to describe anomalous fluctuations and apply it to a class of stochastic cellular automata. The cellular automata, which have been solved microscopically, conserve a charge and it has been demonstrated that the charge fluctuations in these systems and the spin fluctuations in the easy-axis Heisenberg chain are both anomalous with the same non-Gaussian probability distribution function. I will show how our approach successfully reproduces the known typical and large charge fluctuations in the systems and explain how one can understand the phenomena hydrodynamically in systems with a Z_2 charge.

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Tue 18 Feb 14:00: Physical-Layer Security of Satellite Communications Links

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 09:09
Physical-Layer Security of Satellite Communications Links

In recent years, building and launching satellites has become considerably cheaper, making satellite systems more accessible to an expanding user base. This accessibility has led to a diverse array of applications—such as navigation, communications, and earth observation—that depend on satellites. However, hardware limitations and operational considerations often render cryptographic solutions impractical for these systems. Furthermore, the availability of low-cost software-defined radios has made signal capture, injection, and interference attacks more attainable for a wider range of potential attackers.

Therefore, mitigations must be developed for satellites that have already been launched without adequate protections in place. This talk introduces some of our research into how satellite systems are vulnerable, as well as ways to protect these systems.

Bio: Simon Birnbach is a Senior Research Associate and a Royal Academy of Engineering UK IC Postdoctoral Research Fellow in the Systems Security Lab of Professor Ivan Martinovic in the Department of Computer Science at the University of Oxford. He specialises in the security of cyber-physical systems, with a focus on smart home, aviation, and aerospace security.

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Thu 15 May 14:00: Creation of Chemical Complexity via Controlled Functionalization of Organoboron Compounds

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 09:06
Creation of Chemical Complexity via Controlled Functionalization of Organoboron Compounds

Novel reactivities of organoboron compounds have been identified as a source for creating new chemical spaces with functional value. Previously uncharted approaches of activation including, non-covalent interactions, electrochemical redox processes, and photoexcitation have been exploited for the functionalization of organoboron compounds. Combined experimental and computational studies provide insight into the fundamental understanding of the process. Special emphasis of the research program has been devoted to the formation of products with stereochemically-enriched C(sp3) center.

References [1] Go, S. Y.; Chung, H.; Shin, S. J.; An, S.; Youn, J. H.; Im, T. Y.; Kim, J. Y.; Chung, T. D.; Lee, H. G. J. Am. Chem. Soc. 2022, 144, 9149. [2] Roh, B.; Farah, A. O.; Kim, B.; Feoktistova, T.; Moller, F.; Cheong, P. H.; Lee, H. G. J. Am. Chem. Soc. 2023, 145, 7075. [3] Koo, J.; Kim, W.; Jhun, B. H.; Park, S.; Song, D.; You, Y.; Lee, H. G. J. Am. Chem. Soc. 2024, 146, 22874.

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Tue 11 Feb 14:00: Designing Counter Strategies against Online Harms

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 08:59
Designing Counter Strategies against Online Harms

Common mitigation strategies to combat harmful speech online, such as reporting and blocking, are often insufficient as they are reactive, involve unethical human labour and impose censorship. This explores alternative counter strategies such as a quarantining tool and automated counterspeech generator. Quarantining online hate speech and disinformation like a computer virus gives power to the individual user, while a counterspeech generator is specifically designed to produce diverse counter responses to different forms of online harm. Both strategies can protect users from harm and significantly ease the burden of human counterspeakers. The talk will explore the benefits as well as current shortcomings of these strategies and discuss necessary further developments.

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Wed 05 Feb 11:15: Emergent phenomena in nanosculpted devices of quantum materials

http://talks.cam.ac.uk/show/rss/5408 - Tue, 04/02/2025 - 08:36
Emergent phenomena in nanosculpted devices of quantum materials

Electrons typically traverse a conductive medium in a diffusive manner, resulting in a linear relationship between the measured voltage and applied current – known as Ohm’s law. However, violations of Ohm’s law may be found when the inherent symmetries of the underlying system are broken. Examples include the sliding motion of density waves; ballistic or hydrodynamic electron transport; or the symmetry-breaking realised by lattice or magnetic order. Focused ion beam (FIB) fabrication methods enable precise nanoscale devices to be fashioned from high-quality single crystalline materials, ideal for exploring these nonlinear phenomena. Such nanoengineering offers vast potential for the investigation of both fundamental physics and the development novel quantum devices. In this talk, I will introduce three specific examples. Firstly, we will explore the current-induced sliding motion of a skyrmion lattice in Gd2PdSi3 and the resulting emergent electrodynamics, which originate from a time-dependent Berry phase. Secondly, I will highlight our latest breakthrough to develop FIB fabrication of three dimensional nanostructures, in the form of helical-shaped devices of the high-mobility Weyl magnet CoSn2S2. By breaking inversion symmetry on the length scale of the electron mean free path, we observe large nonreciprocal transport, resulting in a switchable diode effect. Finally, if time permits, I will discuss the possibility to fabricate highly symmetrical devices, which allows the probing of symmetry breaking along multiple directions of a material simultaneously – in this case exploited to study signatures of p-wave magnetism in Gd3Ru4Al12.

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Latest news

We are hiring!

4 January 2021

We are seeking to hire a research assistant to work on carbon nanotube based microdevices. More information is available here: www.jobs.cam.ac.uk/job/28202/

We are Hiring!

4 January 2021

We are seeking to hire a postdoc researcher to work on the structuring of Li-ion battery electrodes. More information is available here: www.jobs.cam.ac.uk/job/28197/