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NanoManufacturing

Michael De Volder, Engineering Department - IfM
 

Exclusive Encapsulation Adhesive in a Neutral‐Plane Model for Ultrahigh Mechanical Stability of Flexible Perovskite Solar Cells

The detachment behavior between the adhesives and the electrodes are always caused by significant interlayer shear stress during bending in neutral plane flexible perovskite solar cells (NP-FPSCs). A crosslinkable polymer named acrylated isoprene rubber (AIR) is introduced to form a stable network, ensuring a strong bond between the protective layer and FPSCs. The resultant NP-FPSCs demonstrate excellent mechanical stability — the most mechanically stable devices reported to date.


Abstract

The functional layers of flexible perovskite solar cells (FPSCs) are subjected to significant stress during bending, causing structural failure and declining power conversion efficiency. To alleviate stress, a neutral plane (NP) is introduced by positioning the functional layers at the center of the device, with top metal electrode encapsulated by a protective layer. However, adhesive detachment remains a critical issue during multiple bending cycles, and the underlying mechanism remains unclear. In this study, a systematic analysis of the detachment behavior in NP-FPSC reveals that commercial adhesives with high Young's modulus and low adhesion strength struggle to withstand interlayer shear stress during bending, which triggers detachment between adhesives and electrodes. To address this issue, a crosslinkable polymer acrylated isoprene rubber (AIR) is designed with long linear polyisoprene main chain and acrylate side chains, providing high flexibility and reduced chain segment movement. AIR can be crosslinked under UV irradiation to form a stable network with ultralow Young's modulus and high adhesion strength, ensuring a strong bond between the protective layer and FPSCs, constructing stable NP-FPSCs. The resultant NP-FPSCs demonstrate excellent mechanical stability, retaining 92.8% of their initial efficiency after 50 000 bending cycles at a radius of 4 mm, meeting the IEC 62715-6-3 standards.

Deep Reconstruction of RuPdOx Hollow Nanofibers for Efficient Electrocatalytic Hydrazine Oxidation‐Assisted Hydrogen Production

A rapid and deep reconstruction of RuPdOx hollow nanofibers to generate RuO2/Pd heterostructure is achieved to regulate the local electronic environment of catalyst during hydrogen evolution reaction (HER) and hydrazine oxidation reaction (HzOR) processes. Thus the obtained material exhibits exceptional ampere-grade-current-density HER and HzOR properties, enabling significnat energy-saving H2 production performance.


Abstract

Manipulating the reconstruction of a heterostructured material is highly desirable to achieve high-performance electrocatalytic performance. Here, an in situ reconstruction of RuPdOx hollow nanofibers (HNFs) is presented to generate RuO2/Pd from both the electrochemical and chemical reconstruction processes. The reconstructed catalyst is highly efficient for both hydrazine oxidation reaction (HzOR) and hydrogen evolution reaction (HER) at industrial-grade current densities, significantly outperforming the benchmark Pt/C catalyst. Furthermore, it maintains a record-breaking durability of 500 h for HzOR at 1 A cm−2. Remarkably, with the catalyst as electrodes, a two-electrode overall hydrazine splitting (OHzS) cell is constructed, which requires only 0.263 kWh of electricity to produce 1 m3 H2 at 100 mA cm−2, significantly lower than that in overall water splitting (OWS) system (4.286 kWh m−3 H2), exhibiting an exceptional energy-saving H2 production property. Density functional theory (DFT) calculations reveal an efficient electron transfer from Pd to RuO2 at their interface from the reconstruction of RuPdOx HNFs, which regulates the local electronic environment of atoms, modulates the adsorption and desorption for intermediates, and reduces the energy barriers for enhancing the electrocatalytic process. This study offers a robust reconstruction strategy for the design of electrocatalysts that exhibit superior efficiency in energy conversion devices.

Origami Crawlers: Exploring A Single Origami Vertex for Complex Path Navigation

This study demonstrates that the nonlinear kinematics of origami sheets can be exploited to realize crawlers capable of multimodal locomotion under a single actuation input. In particular, it focuses on one of the simplest origami building blocks - a rigid degree-four vertex - and identifies designs that enable movement in a straight line as well as turning left or right by simply controlling the folding range of the actuated fold.


Abstract

The ancient art of origami, traditionally used to transform simple sheets into intricate objects, also holds potential for diverse engineering applications, such as shape morphing and robotics. In this study, it is demonstrated that one of the most basic origami structures–a rigid, foldable degree-four vertex–can be engineered to create a crawler capable of navigating complex paths using only a single input. Through a combination of experimental studies and modeling, it is shown that modifying the geometry of a degree-four vertex enables sheets to move either in a straight line or turn. Furthermore, it is illustrated that leveraging the nonlinearities in folding allows the design of crawlers that can switch between moving straight and turning. Remarkably, these crawling modes can be controlled by adjusting the range of the folding angle's actuation. This study opens avenues for simple machines that can follow intricate trajectories with minimal actuation.

Designing the Self‐Assembly of Disordered Materials Via Color Frustration

What if disorder can be designed? This work introduces a strategy to self-assemble amorphous materials by designing bonding rules for patchy particles that suppress crystallinity and promote frustration. The designer particles nucleate a network of dodecahedral cages from the liquid, yielding a novel equilibrium amorphous phase. This approach redefines how disorder and function can be programmed at the colloidal scale.


Abstract

The ability to control self-assembly with atomic-level precision has led to remarkable advances in the rational design of crystalline materials. However, similar design strategies have yet to be developed for amorphous materials. Here, a strategy is devised for programming the self-assembly of amorphous structures by encoding frustration into the building block design. The building blocks are tailored to locally favor the formation of five-member rings and yield a network of face-sharing dodecahedral cages whose icosahedral symmetry prevents long-range order. Surprisingly, unlike geometrically frustrated glasses that form through kinetic arrest, the network nucleates spontaneously from the liquid phase, representing a novel type of thermodynamically stable disordered phase. The stabilization of this frustrated phase via programmable interactions paves the way for a new generation of disordered materials.

Morphotropic Phase Boundary in Irradiated Ferroelectric Polymers

Irradiation rather than composition is used to induce helix/trans morphotropic phase boundary (MPB) in ferroelectric polymers. Markedly enhanced piezoelectric coefficient d 33 of -69.8 pC N−1 is achieved in ferroelectric poly(vinylidene fluoride-co-trifluoroethylene) copolymers. This postprocessing approach is generally applicable to different ferroelectric polymer compositions and sources of irradiation, offering a scalable tool to design of ferroelectric polymers with high piezoelectric properties.


Abstract

Morphotropic phase boundary (MPB) enables a large piezoelectric effect in ferroelectric polymers. However, till now MPB has only been observed in a few polymers, which is induced by compositional tuning of the polymer composition. Here a distinct approach to design MPB in ferroelectric polymers is reported via ion irradiation. Without changing composition as required by the conventional compositional approach, the formation of helix/trans MPB in ferroelectric polymers is achieved upon increasing the irradiation dose, near which a substantially enhanced piezoelectric coefficient d 33 of -69.8 pC N−1 is observed. The effectiveness of this method is demonstrated by using different sources of irradiation and polymer compositions, which offers a general and scalable postprocessing tool to effectively improve the piezoelectric response of ferroelectric polymers.

Enhanced Kinetics and Stability of Zn‐MnO2 Batteries with a Multifunctional TiO2 Coating

The TiO2-coated MnO2 cathodes enhance the cycling stability and capacity of zinc-ion batteries by improving kinetics and inhibiting Mn dissolution. The multifunctional TiO2 coating forms a coherent interface with MnO2, creating an electron-enriched surface that promotes rapid electron/ion transport and proton-dominated reactions. Additionally, the coating mitigates Mn dissolution and buffers volume changes, offering a promising solution for advanced energy storage.


Abstract

Zinc-ion batteries are a promising energy storage alternative, offering safety, cost-effectiveness, and environment-friendliness. MnO2 is appealing for its high capacity and output voltage, but it suffers from slow kinetics and poor stability due to severe Mn dissolution during cycling. Here, the performance of MnO2 is enhanced by coating it with a uniform TiO2 nanolayer that incorporates oxygen vacancies. The TiO2-MnO2 heterogeneous interface results in the formation of Ti─O─Mn bonds and a reduction in the interfacial valence state, thereby leading to the creation of an interface electron-enriched region that facilitates faster electron and ion transport. This multifunctional TiO2 coating not only promotes proton-dominated electrochemical reactions and ion diffusion but also acts as a protective barrier, preventing Mn dissolution and buffering volume changes during cycling. Consequently, the MnO2@TiO2 cathode demonstrates excellent specific capacity (299 mAh g−1 at 0.1 A g−1) and cycling stability, achieving 91.4% capacity retention after 2500 cycles at 1 A g−1 and 92.7% capacity retention after 600 cycles at a low current density of 0.2 A g−1. These results outperform many previously reported manganese-based cathodes, demonstrating MnO2@TiO2’s potential as a high-performance and durable cathode material for zinc-ion batteries and advancing the development of efficient energy storage solutions.

Efficient Cu─Co Dual‐Sites in Cobalt Oxide Nanoboxes for Electrocatalytic Reduction of Low‐Concentration NO to NH3

Electrochemical reduction of low-concentration NO presents a promising avenue for NH3 production, offering a sustainable solution to environmental challenges. Cu─Co dual-sites in hollow cobalt oxide nanoboxes are developed for NO electroreduction, boasting a Faraday efficiency of 94.13% and an NH3 yield of 54.28 µg h−1 mgcat −1. A Zn-NO battery has also been successfully demonstrated for simultaneous NO elimination, NH3 generation, and power output.


Abstract

The electrocatalytic conversion of nitric oxide (NO) to ammonia (NH3) epitomizes an advanced approach in NH3 synthesis, crucial for efficiently converting low-concentration industrial NO exhaust and contributing significantly to environmental preservation. Catalyst design remains one pivotal element in addressing this challenge. Here, efficient Cu─Co dual active sites embedded in hollow cobalt oxide nanoboxes are created for the electrocatalytic low-concentration NO reduction reaction (NORR). Cu-modified cobalt oxide (Cu-Co3O4) and its heterophase interface with copper oxide (Cu-Co3O4/CuO) both exhibit over 93% Faraday efficiency for NH3 synthesis, with a yield reaching up to 59.10 µg h−1 mgcat −1 at −0.4 V versus reversible hydrogen electrode by utilizing simulated industrial NO exhaust (1 vol %) as the feedstock, surpassing those of pure cobalt oxide and some reported catalysts. Theoretical calculations and NO temperature-programmed desorption experiments demonstrate that the incorporation of Cu significantly enhances NO adsorption and reduces the energy barrier of the rate-determining step. The integration of Cu-Co3O4 and Cu-Co3O4/CuO within the cathode of the Zn–NO battery demonstrates a notable power density of 2.02 mW cm−2, highlighting a propitious direction for investigating highly efficient conversion of low-concentration NO exhaust gas.

Effect of Combination Model of MoTe2 and MXene Layers on Sodium Ion Storage

Compared with MX@MoTe2-V, in which the (002) crystal plane of MoTe2 is perpendicular to the MXene layer, MX@MoTe2-P with MoTe2 (002) crystal plane parallel to MXene layer has a more stable interface structure and more sodium ion storage sites, thereby achieving excellent electrochemical performance.


Abstract

The integration of different crystal planes between two-dimensional (2D) materials results in various combinations, which always exert different effects on the electrochemical properties of materials. The metallic 1T′ phase of molybdenum telluride is a promising anode for sodium-ion batteries (SIBs), but its rearrangement and restacking during charge/discharge process causes a decline in cycle. Herein, MX@MoTe2-P with MoTe2 (002) planes parallel to MXene layers and MX@MoTe2-V with MoTe2 (002) planes perpendicular to MXene layers are controllably constructed. Compared with MX@MoTe2-V, the new interface formed between MoTe2 and MXene in MX@MoTe2-P has a stronger van der Waals interaction and larger contact area, helpful to store more sodium ions and contributing to its excellent structural stability and battery capacity. Although MX@MoTe2-V has a higher sodium adsorption energy than MX@MoTe2-P, the small interface area lowers the storage capacity and it further aggravates the collapse of the structure. When used as the anode for SIBs, MX@MoTe2-P offers excellent cycle stability and specific capacity. In particular, sodium-ion full cell consisting of MX@MoTe2-P anode and Na3V2(PO4)3 cathode shows the excellent performance (147.2 mAh g−1@1000 cycles at 5 A g−1) surpassing all the reported MoTe2-based materials. This work provides a guide for the manufacture of new electrode materials.

Nanozyme‐Reinforced Hydrogel Spray as a Reactive Oxygen Species‐Driven Oxygenator to Accelerate Diabetic Wound Healing

The authors fabricate a reactive oxygen species-driven oxygenation hydrogel (OxyGel) spray, which can rebalance the oxidative and hypoxic microenvironment of the diabetic wound, promote M1-to-M2 macrophage repolarization, and enhance the survival, migration, and angiogenesis of endothelial cells. A single administration of the OxyGel spray accelerates full-thickness back skin wound and refractory foot ulcer wound healing in diabetic rats.


Abstract

The accumulation of reactive oxygen species (ROS) and poor oxygen supply are two prominent factors of the inflammatory microenvironment that delay diabetic wound healing. However, current clinical treatments cannot achieve effective ROS scavenging and sustained oxygenation. Herein, a ROS-driven oxygenation hydrogel (OxyGel) spray that integrates a multifunctional nanozyme with a dynamically crosslinked sprayable hydrogel matrix is presented. The nanozyme, which is fabricated based on the ceria-zoledronic acid nanoparticles modified with tannic acid (TCZ nanozymes), can mimic the cascade catalytic activities of superoxide dismutase (SOD) and catalase (CAT) to effectively scavenge ROS while generating oxygen. These synergistic actions rebalance the oxidative and hypoxic microenvironment of the diabetic wound, promote M1-to-M2 macrophage repolarization, and enhance the survival, migration, and angiogenesis of endothelial cells. A single administration of the nanozyme via the hydrogel spray stably deposits the nanozymes at the target sites to accelerate full-thickness back skin wound and refractory foot ulcer wound healing in diabetic rats. Furthermore, RNA-seq results revealed the upregulation of multiple signaling pathways related to wound healing by the OxyGel spray, highlighting the potential of this platform not only for the treatment of refractory diabetic wounds but also other diseases associated with oxidative stress and hypoxia.

Crystalline‐Dependent Magnon Torques in All‐Sputtered Hf/Cr2O3/Ferromagnet Heterostructures

Magnon torques can overcome the Joule heating issue in traditional spintronic devices. The crystalline dependence of magnon torques in Hf/Cr2O3/FM heterostructures is demonstrated. Magnon torques are generated when the Néel vector of Cr2O3 is parallel to the spin polarization generated in Hf. Furthermore, the magnetization switching of perpendicularly magnetized CoFeB is achieved using magnon torques.


Abstract

Electron motion in spin-orbit torque devices inevitably leads to the Joule heating issue. Magnon torques can potentially circumvent this issue, as it enables the transport of spin angular momentum in insulating magnetic materials. In this work, a sandwich structure composed of Hf/antiferromagnetic Cr2O3/ferromagnet is fabricated and demonstrates that the magnon torque is strongly dependent on the crystalline structure of Cr2O3. Magnon torques are stronger when the Néel vector of Cr2O3 aligns parallel to the spin polarization generated in Hf, while they are suppressed when the Néel vector is perpendicular to the spin polarization. The magnon torque efficiency is estimated to be −0.134 using in-plane second harmonic Hall measurements. Using magnon torques, perpendicular magnetization switching of CoFeB is achieved, with a critical switching current density of 4.09 × 107 A cm−2. Furthermore, the spin angular momentum loss due to the insertion of Cr2O3 is found to be lower than that of polycrystalline NiO. The work highlights the role of antiferromagnet crystalline structures in controlling magnon torques, broadening the potential applications of magnon torques.

Spin‐Splitting Magnetoresistance in Altermagnetic RuO2 Thin Films

A novel magnetoresistance effect termed spin-splitting magnetoresistance (SSMR) is demonstrated in (101)-RuO2/Co bilayers. The SSMR is underpinned by the spin–charge interconversion process induced by the nonrelativistic spin-splitting effect in altermagnets. Utilizing the SSMR, a [001]-oriented Néel vector in an epitaxial thin film of RuO2 is revealed, which evidences its altermagnetism.


Abstract

The recently discovered altermagnets, featured by the exotic correlation of magnetic exchange interaction and alternating crystal environments, have offered exciting cutting-edge opportunities for spintronics. Nevertheless, the altermagnetism of RuO2, one of the earliest-discovered altermagnets, is currently under intense debate. Here, this controversy is attempted to be resolved by demonstrating a spin-splitting magnetoresistance (SSMR) effect that is driven by a spin current associated with the giant nonrelativistic spin splitting of an altermagnet. Compared to the spin Hall magnetoresistance induced by a conventional relativistic spin current, the SSMR is characterized by unusual angular dependence with a phase-shift feature underpinned by the Néel-vector orientation and pronounced temperature dependence caused by its susceptibility to electron scattering. Through systematical investigations on the magnetoresistance of (101)-RuO2/Co bilayers, a sizable SSMR is disentangled and hence a Néel vector along [001] direction is unveiled. This work not only demonstrates a simple electric avenue for probing the Néel vector of altermagnets, but also indicates long-range magnetic order in thin films of RuO2.

Native Defect Elimination and Lattice Framework Reinforcement Toward Ultra‐Stable Sodium‐Ion Layered Cathodes

Conventional solid-phase sintered samples have native surface defects, mainly consisting of lattice mismatches and elemental distortions, and pose problems of TM dissolution and crack growth during subsequent cycles. With an understanding of the spatial distribution of the defects and an appreciation of the importance of the surface state, a strategy of surface defect elimination and crystal framework enhancement is applied and demonstrated to provide strong stability of the cathodes treated by this strategy.


Abstract

Structural and performance degradation in layered transition metal oxide (TMO) cathode materials is often attributed to phase transition induction during sodium de-embedding, while the significance of native defects during complex synthesis is frequently overlooked. Here, the role of native surface remodeling in progressive capacity degradation in P2-type Na2/3Ni1/3Mn2/3O2 is emphasized, where lattice mismatches and elemental distortions are found on the surface of the particles and result in the accumulation of low-valent TMs. Interestingly, the accumulation gradually became the center of cathodic degradation rather than phase transition induction. Given the apparent spatiality of the primary defects and recognizing the importance of the surface state, the stripping repair of the defects and gradient introduction of La can be manipulated. The unique LaO6 configuration enhanced the rigid framework of TMO6 and suppressed the emergence of low-valent TMs, resulting in surface-corrected and reinforced particles, which can be explained by generalized functional density calculations and ex-situ hard X-ray absorption spectroscopy. As a result, the reinforced cathode brought about a capacity retention of up to 98% for 500 cycles at 2 C and 87% for 4000 cycles at 10 C and stable electrochemical performance over a wide temperature range (−20 °C–60 °C).

Highly Robust and Conductive Polymer Electrodes for Droplet Energy Harvesting and Printable On‐Skin Electronics

A bi-continuous polymer electrode (BC-PE) is developed by using PBFDO as the electrical phase and TPU as the mechanical phase, featuring exceptional properties including high conductivity, mechanical toughness, robustness, stretchability, stability, recyclability, and biocompatibility. Leveraging the capabilities of the BC-PE, a record high-performance droplet electricity generator and a self-powered electronic skin for the human-machine interface are achieved.


Abstract

Solution-processable conductive polymers have exhibited promising electrical properties. However, their brittleness and unsatisfactory mechanical characteristics have hindered their creation of flexible electrodes. Here, a robust bi-continuous polymer electrode (BC-PE) is reported that features a stable and high electrical conductivity (>60 S cm−1), remarkable stretchability (>600%), high fracture strength (>57 MPa), excellent toughness (>230 MJ m−3), recyclability, and biocompatibility. The BC-PE is fabricated by facilely blending a high-conducting polymer poly(benzodifurandione)(PBFDO) with thermoplastic polyurethane (TPU). Serving as a flexible electrode for a droplet electricity generator, a record high current density of 29.2 A m−2 and a power density of 1124.2 W m−2 have been attained. Moreover, the versatility of the BC-PE is validated by the direct ink writing technique, and a soft, thin, BC-PE-based self-powered electronic skin is demonstrated for touch-track recognition. This work presents a straightforward strategy for the development of advanced conductive polymer electrodes that well address the tradeoffs between conductivity and mechanical properties, showcasing their promising applications in energy harvesting and on-skin human-machine interfaces.

Designing an Anionic Layer in Low‐Concentration Electrolytes to Promote In‐Plane Ion Diffusion for Dendrite‐Free Zinc‐Ion Batteries

An optimization model for zinc anodes centered on anion traction in a low-concentration electrolyte system is proposed. The fluoride-ion enriched interfacial layer on the zinc anode surface enhances the concentration of Zn2+ in a lateral direction through electrostatic forces, thereby facilitating horizontal zinc plating. Moreover, the repulsion between the anion-rich layer and sulfate ions can effectively inhibit the formation of byproducts.


Abstract

In contrast to high-concentration electrolyte systems, low-concentration electrolytes provide a cost-effective strategy to advance the commercialization of aqueous zinc-ion batteries (AZIBs). However, such electrolytes frequently exhibit severe dendrite formation caused by localized Zn2+ concentration gradients, which critically compromise the cycling stability and operational safety of AZIBs. In this work, an innovative approach is proposed that involves the in situ construction of a fluoride-ion (F−) enriched interfacial layer on zinc anodes. This method facilitates in-plane diffusion of zinc ions at the anode interface, resulting in accelerated lateral growth of zinc deposits rather than dendritic formation. The results indicate that this orientated growth is closely associated with an anionic layer that effectively reduces random and irregular deposition as well as undesirable side reactions. The proposed system exhibits exceptional electrochemical performance within a low-concentration electrolyte framework, achieving a battery lifespan exceeding 1500 h at a current density of 2 mA cm−2. Furthermore, it maintains Coulombic efficiency above 99% after 800 h of cycling. Additionally, the Na2V6O16·3H2O (NVO)//Zn full battery incorporating this additive showcases enhanced long-term cycling performance and improved capacity retention, further confirming the excellent reversibility of the plating/stripping processes for zinc anode.

Mon 04 Aug 11:00: Learning Under Constraints: From Federated Collaboration to Black-Box LLMs

http://talks.cam.ac.uk/show/rss/5408 - Tue, 10/06/2025 - 14:33
Learning Under Constraints: From Federated Collaboration to Black-Box LLMs

In both federated learning (FL) and large language model (LLMs) optimization, a central challenge is effective learning under constraints, ranging from data heterogeneity and personalization to limited communication and black-box access. In this talk, I present three approaches that address these challenges across different settings. FilFL improves generalization in FL by filtering clients based on their joint contribution to global performance. DPFL tackles decentralized personalization by learning asymmetric collaboration graphs under strict resource budgets. Moving beyond FL, I will present ACING , a reinforcement learning method for optimizing instructions in black-box LLMs under strict query budgets, where weights and gradients are inaccessible. While these works tackle distinct problems, they are unified by a common goal: developing efficient learning mechanisms that perform reliably under real-world constraints.

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Wed 16 Jul 16:00: Condensing the Message: How Notch Signaling Forms Transcriptional Hubs to Control Gene Activation

http://talks.cam.ac.uk/show/rss/5408 - Tue, 10/06/2025 - 12:30
Condensing the Message: How Notch Signaling Forms Transcriptional Hubs to Control Gene Activation

Developmental decisions rely on cells making accurate transcriptional responses to signals they receive. For example, Notch pathway activity results in rapid transcriptional outputs in the absence of any amplification steps. Local condensates or transcription factor hubs are proposed to facilitate recruitment of key nuclear complexes and their co-factors to promote gene activation. To investigate whether transcription hubs are formed under conditions of endogenous Notch signalling, we combined real-time measurements of Notch transcription-complex enrichments relative to a fluorescently tagged gene locus with quantitative live imaging of gene transcription from two linked loci. An enriched hub containing the co-activator Mastermind (Mam) was formed in a signalling-dependent manner during developmental stages when transcription occurs. Tracking hubs in real time revealed that they are highly dynamic and, when imaged together with transcription in the same nucleus, Mam condensation consistently correlates with the onset and profile of transcription. Manipulations affecting signalling levels had concordant effects on hub intensities and transcriptional profiles, altering the probability and amplitude of transcription. Together the results support a model in which signalling induces the formation of transcription hubs whose properties are instrumental in the quantitative gene expression response to Notch activation.

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Wed 16 Jul 16:00: Hox Activity Levels Govern the Evolution of Behaviors

http://talks.cam.ac.uk/show/rss/5408 - Tue, 10/06/2025 - 12:10
Hox Activity Levels Govern the Evolution of Behaviors

Despite being a fundamental question in Biology, the evolution of animal behaviour remains poorly understood. The divergence of behaviours has been correlated with neuronal circuit changes between species or with distinct genetic makeups, but actual demonstrations of the genetic processes that have taken place to drive the emergence of new behaviours have only been achieved in the sensory system in the context of receptor expression (Auer et al., Nature 2020). Here, we show that by merely tweaking the levels of expression of the key developmental Hox genes, different circuits with different behavioural outputs can be generated. This change occurs only at the final steps of embryonic development, refining connectivity in an otherwise unchanged system. In other words, rather than requiring specific developmental blueprints for each motor circuit—in the case of the fruit fly, those governing, rolling, turning, crawling, etc.—a single blueprint is used, with gene expression levels at the final stages determining the final designation of each circuit. Such a mechanism ensures the system stability and simplifies circuit diversification—within organisms and potentially also across all organisms.

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Interfacial Engineering of Dopant-Free Phthalocyanine Hole Transporters for >22% Efficiency Perovskite Solar Modules

http://feeds.rsc.org/rss/ee - Tue, 10/06/2025 - 11:44
Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5EE00120J, PaperZhen-Yang Suo, Xijiao Mu, Chong Chen, Guobin Xiao, Jing Cao
The instability of doped Spiro-OMeTAD, a widely used hole transport material (HTM), hinders the industrial progress of n-i-p structured perovskite photovoltaics. Phthalocyanines, known for their stability as HTMs, present a...
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Mon 16 Jun 14:00: Polyhomogeneity and precise asymptotic expansions for quasilinear waves scattering from past to future null infinity, with applications to general relativity

http://talks.cam.ac.uk/show/rss/5408 - Tue, 10/06/2025 - 10:45
Polyhomogeneity and precise asymptotic expansions for quasilinear waves scattering from past to future null infinity, with applications to general relativity

Already for the linear wave equation on the Minkowski spacetime, scattering solutions arising from data in the infinite past (at “past null infinity”) have surprisingly different asymptotic behaviour towards future null infinity depending on both the dimension and on the nature of the scattering data. In this talk, I will explain and prove these differences, and I will then sketch how to more generally determine the asymptotics towards future null infinity for a much wider class of quasilinear equations.

In the context of the Einstein equations of general relativity, this work allows to determine the asymptotics of gravitational radiation, and thus the smoothness of null infinity, in physically realistic scattering scenarios.

Based on joint work with Istvan Kadar (Princeton University)

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Fri 06 Feb 08:45: Grand Rounds - soft tissue

http://talks.cam.ac.uk/show/rss/5408 - Tue, 10/06/2025 - 10:36
Grand Rounds - soft tissue

Chaired by Laura Owen

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