Tue 29 Apr 15:15: BSU Seminar: "Investigating complex dependence structures using Bayesian mixture modelling" This will be a free hybrid seminar. To register to attend virtually, please click here: https://cam-ac-uk.zoom.us/meeting/register...
We investigate complex dependence structures between categorical variables. We utilise Bayesian partitioning on subjects and variables simultaneously, referring to clusters of variables as views. We incorporate a variable selection procedure that highlights the variables that drive the clustering of the subjects within each view. We derive theoretical results on the relation between the variables’ dependence structure and the inferences derived from the implemented clustering. We demonstrate how such clustering results can be used to assist loglinear graphical model determination with simulated and real data sets.
This will be a free hybrid seminar. To register to attend virtually, please click here: https://cam-ac-uk.zoom.us/meeting/register/7PLSTFN7QM6iUvdzQaegEw
- Speaker: Dr Michail Papathomas, University of St Andrews
- Tuesday 29 April 2025, 15:15-16:15
- Venue: Large Seminar Room, East Forvie Building, Forvie Site Robinson Way Cambridge CB2 0SR..
- Series: MRC Biostatistics Unit Seminars; organiser: Alison Quenault.
Fri 13 Jun 15:30: Science advice under uncertainty
In this session, Amy Orben, the leader of the Digital Mental Health Group at the MRC Cognition and Brain Sciences Unit, will talk about her experience of having to support evidence-based policy in the area of teen mental health and social media. Her vision on how this could be improved was described in Orben, Amy, and J. Nathan Matias, ‘Fixing the science of digital technology harms’, Science 388, no. 6743 (2025): 152–155.
- Speaker: Amy Orben (MRC Cognition and Brain Sciences Unit)
- Friday 13 June 2025, 15:30-17:00
- Venue: Seminar Room 2, Department of History and Philosophy of Science.
- Series: Coffee with Scientists; organiser: Marta Halina.
Fri 16 May 14:00: Title to be confirmed
Abstract not available
- Speaker: Professor Dan V Nicolau, McGill University
- Friday 16 May 2025, 14:00-15:00
- Venue: Oatley 1 Meeting Room, Department of Engineering.
- Series: Engineering - Mechanics and Materials Seminar Series; organiser: div-c.
Fri 30 May 15:30: The Culture Lab
Abstract not available
- Speaker: Helene Scott-Fordsmand (Clare Hall & HPS, Cambridge) and Anatolii Kozlov (Science & Technology Studies, UCL)
- Friday 30 May 2025, 15:30-17:00
- Venue: Seminar Room 2, Department of History and Philosophy of Science.
- Series: Coffee with Scientists; organiser: Marta Halina.
One-Stone-Two-Birds: Over 26% Efficiency in Perovskite Solar Cells via Synergistic Crystallization & Interface Regulation
DOI: 10.1039/D5EE00189G, PaperBoxin Jiao, Liguo Tan, Yiran Ye, Ningyu Ren, Minghao Li, Hang Li, Xiaoyi Li, Chenyi Yi
Organic-inorganic hybrid perovskites have emerged as promising photovoltaic materials due to their excellent photoelectronic properties and low-cost fabrication techniques. However, the performance and stability of perovskite solar cells (PSCs) are...
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Tue 29 Apr 14:00: BSU Seminar: "Common atoms mixture models in some biostatistical inference problems" This will be a free hybrid seminar. To register to attend virtually, please click here: https://cam-ac-uk.zoom.us/meeting/register...
We consider several examples of statistical inference for two or more related populations. In one example we characterize two patient populations that are relevant in the construction of a clinical study design, and propose a method to adjust for detected differences. Another example is about comparative immune profiling under two biologic conditions of interest when we identify shared versus condition-specific homogeneous cell subpopulations. In a third example we model spatially aligned cell subpopulations for spatial transcriptomics data.
Bayesian inference in all three applications requires prior probability models for two or more related distributions. We build on extensive literature on such models based on Dirichlet process priors. Related models are commonly known as dependent Dirichlet processes (DDP), with many variations and extensions beyond the Dirichlet process model.
One special feature in all three motivating applications is the focus on understanding the nature of the dependence across the related populations. In one application we aim to adjust for differences in population heterogeneity, in another we aim to identify and understand homogeneous subpopulations that are characteristic for one or the other condition.
This will be a free hybrid seminar. To register to attend virtually, please click here: https://cam-ac-uk.zoom.us/meeting/register/4uUskN5ZQjaJzckpMbxQ1Q
- Speaker: Prof Peter Mueller, University of Texas
- Tuesday 29 April 2025, 14:00-15:00
- Venue: Large Seminar Room, East Forvie Building, Forvie Site Robinson Way Cambridge CB2 0SR..
- Series: MRC Biostatistics Unit Seminars; organiser: Alison Quenault.
Thu 08 May 11:30: TBC
Abstract not available
- Speaker: Emma Lepinay, IEEF
- Thursday 08 May 2025, 11:30-12:30
- Venue: Open Plan Area, Institute for Energy and Environmental Flows, Madingley Rise CB3 0EZ.
- Series: Institute for Energy and Environmental Flows (IEEF); organiser: Catherine Pearson.
Thu 01 May 11:30: Interaction of Mechanical Ventilation and Natural Convection
Abstract not available
- Speaker: Dan Toy, IEEF
- Thursday 01 May 2025, 11:30-12:30
- Venue: Open Plan Area, Institute for Energy and Environmental Flows, Madingley Rise CB3 0EZ.
- Series: Institute for Energy and Environmental Flows (IEEF); organiser: Catherine Pearson.
Tue 13 May 11:00: Single charge pion production cross-sections at MicroBooNE
Single charge pion production cross-sections at MicroBooNE
- Speaker: Philip Detje: Cavendish Laboratory, University of Cambridge
- Tuesday 13 May 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Wed 30 Apr 16:00: Adding Biology to Barcodes: Tackling the Hidden Diversity of the Marine Alveolates Host: Ross Waller
Metabarcoding datasets targeting protists in marine environments are often dominated by a group of dinoflagellates referred to as the Marine Alveolates (MALVs). Despite a global distribution, considerable sequence diversity, and significant prevalence and abundance in various hosts and environments, MAL Vs include just a handful of characterised lineages. They largely represent a vast collection of uncharacterised 18S barcodes. Known lineages, however, are important parasites that can impact fish and crustacean farming or even harmful algal bloom proliferation. Dinoflagellate genomes are notoriously large and complex. With only two comprehensive MALV genomes available, inferring robust evolutionary histories based solely on 18S phylogenies remains challenging. To overcome this issue, we are manually isolating and sequencing individual MALV cells to generate transcriptomes for phylogenomics, increasing the number of characterised MALV lineages and improving our understanding of dinoflagellate evolution in the process. Using this approach, we demonstrated that MAL Vs originated from two distinct, free-living ancestors, indicating multiple transitions to parasitism and challenging prevailing assumptions about MAL Vs as a whole. More recently, we have isolated several new genera, one of which appears to represent an entirely new MALV group. Going forward, we aim to use metabarcoding datasets to guide the targeted isolation of uncharacterised MALV lineages, filling in critical gaps in our understanding of these important regulators of both animal and environmental health.
Host: Ross Waller
- Speaker: Dr Corey Holt, University of Bath
- Wednesday 30 April 2025, 16:00-17:00
- Venue: Seminar Room, Tennis Court Road, Dept of Pathology..
- Series: Parasitology Seminars; organiser: Ross Waller.
Thu 09 Oct 16:00: Inflammation in vaccines and infection: it’s (even) more complex than we think
This Cambridge Immunology and Medicine Seminar will take place on Thursday 9 October 2025, starting at 4:00pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)
Speaker: Prof John Tregoning, Professor of Vaccine Immunology at Imperial College London
Title: ‘Inflammation in vaccines and infection: it’s (even) more complex than we think’
Prof John Tregoning is currently Professor of Vaccine Immunology at Imperial College London, where he has studied the immune responses to vaccination and respiratory infection for more than 25 years. His group is currently focusing on the immune response to RNA vaccination. John has written more than 90 peer-reviewed scientific articles. He is also the author of two books Live Forever? A Curious Scientist’s Guide to Wellness, Disease and Ageing and Infectious: Pathogens and how we fight them.
Host: Ravindra Gupta, CITIID , Cambridge
Refreshments will be available following the seminar.
- Speaker: Prof John Tregoning, Professor of Vaccine Immunology at Imperial College London
- Thursday 09 October 2025, 16:00-17:00
- Venue: Lecture Theatre, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus.
- Series: Cambridge Immunology Network Seminar Series; organiser: Ruth Paton.
Thu 12 Jun 11:30: TBC
Abstract not available
- Speaker: Quentin Kriaa, Uni of Cambridge
- Thursday 12 June 2025, 11:30-12:30
- Venue: Open Plan Area, Institute for Energy and Environmental Flows, Madingley Rise CB3 0EZ.
- Series: Institute for Energy and Environmental Flows (IEEF); organiser: Catherine Pearson.
In Situ Engineering of Grain Boundary Phase toward Superior Thermoelectric Performance in Mg3(Sb,Bi)2
The introduction of grain boundary phases with low resistivity can effectively enhance the thermoelectric performance of Mg3(Sb,Bi)2. This work proposes an in situ engineering approach inducing TiO2-n to reduce interfacial barriers, which is attributed to the formation of Ti3Sb. These secondary phases significantly enhance the power factor while simultaneously reducing the lattice thermal conductivity, thereby resulting in a superior figure of merit (zT) and conversion efficiency.
Abstract
As a promising thermoelectric material for electronic cooling and power generation, Mg3(Sb,Bi)2 has received extensive attention. Despite efforts to enhance its performance through composite modulation, challenges such as secondary phase refinement, dispersion, and interfacial mismatch, particularly at grain boundaries, remain critical. In this work, by incorporating TiO2-n into the Mg3(Sb,Bi)2-based matrix, the grain boundary phases are in situ engineered, yielding a superior figure of merit (zT) exceeding 2 at 798 K. The electrical conductivity is significantly enhanced with only slight changes to the Seebeck coefficient over the entire temperature range, mainly due to the contribution to carrier concentration and mobility from the newly generated Ti3Sb at grain boundaries. Benefiting from the remarkably enhanced power factor and the diminished lattice thermal conductivity, the zT value shows an overall increase within the temperature range of 300–798 K, leading to a considerable conversion efficiency of 15% for the single-leg device.
Superhigh Magnetostriction in Non‐Equilibrium Grown Fe‐Ga Single‐Crystals by Rapid‐Directional‐Solidification
An innovative strategy of rapid-directional-solidification is developed to unexpectedly grow non-equilibrium single-crystals of Fe-Ga magnetostrictive material with the supersaturation of Tb, leading to an unprecedentedly giant magnetostriction of 489 ppm in bulk Fe-Ga single-crystals. This study paves the way for realizing revolutionary material performance by innovating the concept and fabrication method of non-equilibrium single-crystals.
Abstract
The non-equilibrium microstructure characterized by Tb supersaturation within Fe-Ga single-crystals is deduced to induce a substantial enhancement in magnetostriction. However, the growth of the non-equilibrium single-crystal remains a formidable obstacle, as existing methods can only produce either non-equilibrium polycrystal or near-equilibrium single-crystal, leading to the stagnation in magnetostriction. Herein, a rapid-directional-solidification (RDS) strategy is devised to grow non-equilibrium single-crystals. The RDS is realized through achieving an ultrahigh temperature gradient of ≈106 K m−1 at S-L interface front, accompanied by an ultrafast growth velocity. This results in single-crystal growth under non-equilibrium conditions with a giant cooling rate of 102–103 K s−1, which is ≈1–2 orders of magnitude greater than the current state-of-the-art of directional-solidification methods. A non-equilibrium Fe-Ga single-crystal, featured with traces of Tb supersaturation, is successfully grown with a significantly enhanced magnetostriction of 489 ppm. This magnitude of magnetostriction sets a record in bulk Fe-Ga materials, surpassing the maximum value reported for Fe-Ga single-crystals by 60%. The advent of RDS strategy opens an avenue for fabricating non-equilibrium single-crystals with revolutionary performance, and paves the way for fabricating currently unattainable single-crystals for engineering applications.
Tue 10 Jun 11:00: Title to be confirmed
T2K +NOvA Joint Result
- Speaker: Patrick Dunne: Imperial College London
- Tuesday 10 June 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Tue 03 Jun 11:00: Title to be confirmed
Abstract not available
- Speaker: Naomi Cooke: University of Glasgow
- Tuesday 03 June 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Tue 27 May 11:00: Title to be confirmed
Proton Beam Therapy and Diagnostic Detector Research
- Speaker: Simon Jolly: University College London
- Tuesday 27 May 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Tue 20 May 11:00: A general approach to quantum integration of cross sections in high-energy physics
Monte Carlo integration is a fundamental method underpinning Monte Carlo simulations in high-energy physics (HEP). In this talk, I will present universal “building blocks” for quantum-enhanced integration of generic cross sections in HEP , based on Fourier Quantum Monte Carlo Integration. Leveraging Quantinuum’s Quantum Monte Carlo Integration engine, this approach enables the efficient generation of quantum circuits for these calculations, achieving a quadratic speed-up in root mean-squared error convergence compared to classical methods. To illustrate its impact, I will walk through a concrete example of a 1→3 decay process, demonstrating how quantum algorithms can enhance integral estimation in HEP and potentially reshape computational strategies in the future.
- Speaker: Ifan Williams: Quantinuum
- Tuesday 20 May 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Tue 13 May 11:00: Title to be confirmed
Single charge pion production cross-sections at MicroBooNE
- Speaker: Philip Detje: Cavendish Laboratory, University of Cambridge
- Tuesday 13 May 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.
Tue 06 May 11:00: Title to be confirmed
LHCb Upgrade
- Speaker: Dan Thompson: University of Birmingham
- Tuesday 06 May 2025, 11:00-12:00
- Venue: Seminar Room -- RDC D2.002 .
- Series: Cavendish HEP Seminars; organiser: Dr Paul Swallow.