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1) Navigating Digital Health: Sociodemographic and Neuropsychiatric Influences on Youth uptake of Sexual and Reproductive Health Services; 2) Endometriosis and psychiatric comorbidity

1) Telehealth is increasingly becoming an integral part of modern healthcare systems – following the COVID 19 pandemic digital modalities like video and message-based consultations have expanded rapidly. Youth represent a particularly promising demographic for digital healthcare, for whom a key priority is access to sexual and reproductive health (SRH) services. Recent studies suggest that technology-based SRH services are perceived as confidential and private by youth. Still, among young people large-scale studies of population-based uptake remain sparce. However, in the general population digital solutions have been observed to be disproportionally accessed and adopted by more advantaged groups in the general population. Furthermore, comparisons of uptake across different digital modalities remain understudied, and it is unclear whether some might be more equitably accessed across sociodemographic groups than others. In this research project, we leverage Sweden’s unique national registries and health data to examine the dynamics of digital SRH service use among youth. The doctoral project focuses on youth clinics offering free-of-charge sexual and reproductive health services for youth 12-22 in Stockholm, Sweden. Whereas the first article focused on comparing uptake of in-person and digital services across sociodemographic groups (sex, age, migrant background and socioeconomic status), a forthcoming study will examine the uptake among neurotypical and neurodiverse youth (autism spectra and ADHD ).

2) Endometriosis is a common gynecological condition that can lead to chronic pain and infertility. Approximately 1/10 of all women of reproductive age are believed to be affected but underdiagnosis is common. Despite how common and costly the disease is, there is still no complete cure, and we know relatively little about how it develops. Women with endometriosis also have an increased risk of experiencing mental health issues. The most commonly observed comorbidity between endometriosis and psychiatric disorders is depression and anxiety disorders. It has previously largely been seen as a consequence of the chronic pain many endometriosis patients experience as well as the psychological toll of having a chronic disease. There have, however, been several studies, including one from our group, that have shown an increased incidence of other psychiatric disorders, such as bipolar disorder, ADHD , and personality disorders, where the link to pain is much less clear. In our project we want to examine other possible causes for the comorbidity, such as genetics and family environment, that could explain the high prevalence of mental disorders in endometriosis sufferers. To do this we utilize data from large national registers as well as genetic data to try to elucidate exactly how endometriosis and psychiatric disorders are linked.

• Speaker: 1) Lovisa Hellsten 2) Marika Rostvall. Both speakers are from the Karolinska Institutet
• Wednesday 16 April 2025, 11:30-13:00
• Venue: https://us02web.zoom.us/j/87076030035?pwd=XUpJuh8jiR0mae1AhkV79qbg8MtlSM.1.
• Series: ARClub Talks; organiser: Simon Braschi.

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1) Navigating Digital Health: Sociodemographic and Neuropsychiatric Influences on Youth uptake of Sexual and Reproductive Health Services; 2) Endometriosis and psychiatric comorbidity

1) Telehealth is increasingly becoming an integral part of modern healthcare systems – following the COVID 19 pandemic digital modalities like video and message-based consultations have expanded rapidly. Youth represent a particularly promising demographic for digital healthcare, for whom a key priority is access to sexual and reproductive health (SRH) services. Recent studies suggest that technology-based SRH services are perceived as confidential and private by youth. Still, among young people large-scale studies of population-based uptake remain sparce. However, in the general population digital solutions have been observed to be disproportionally accessed and adopted by more advantaged groups in the general population. Furthermore, comparisons of uptake across different digital modalities remain understudied, and it is unclear whether some might be more equitably accessed across sociodemographic groups than others. In this research project, we leverage Sweden’s unique national registries and health data to examine the dynamics of digital SRH service use among youth. The doctoral project focuses on youth clinics offering free-of-charge sexual and reproductive health services for youth 12-22 in Stockholm, Sweden. Whereas the first article focused on comparing uptake of in-person and digital services across sociodemographic groups (sex, age, migrant background and socioeconomic status), a forthcoming study will examine the uptake among neurotypical and neurodiverse youth (autism spectra and ADHD ).

2) Endometriosis is a common gynecological condition that can lead to chronic pain and infertility. Approximately 1/10 of all women of reproductive age are believed to be affected but underdiagnosis is common. Despite how common and costly the disease is, there is still no complete cure, and we know relatively little about how it develops. Women with endometriosis also have an increased risk of experiencing mental health issues. The most commonly observed comorbidity between endometriosis and psychiatric disorders is depression and anxiety disorders. It has previously largely been seen as a consequence of the chronic pain many endometriosis patients experience as well as the psychological toll of having a chronic disease. There have, however, been several studies, including one from our group, that have shown an increased incidence of other psychiatric disorders, such as bipolar disorder, ADHD , and personality disorders, where the link to pain is much less clear. In our project we want to examine other possible causes for the comorbidity, such as genetics and family environment, that could explain the high prevalence of mental disorders in endometriosis sufferers. To do this we utilize data from large national registers as well as genetic data to try to elucidate exactly how endometriosis and psychiatric disorders are linked.

• Speaker: 1) Lovisa Hellsten 2) Marika Rostvall. Both speakers are from the Karolinska Institutet
• Wednesday 16 April 2025, 11:30-13:00
• Venue: https://us02web.zoom.us/j/87076030035?pwd=XUpJuh8jiR0mae1AhkV79qbg8MtlSM.1.
• Series: ARClub Talks; organiser: Simon Braschi.

Add to your calendar or Include in your list

1) Navigating Digital Health: Sociodemographic and Neuropsychiatric Influences on Youth uptake of Sexual and Reproductive Health Services; 2) Endometriosis and psychiatric comorbidity

1) Telehealth is increasingly becoming an integral part of modern healthcare systems – following the COVID 19 pandemic digital modalities like video and message-based consultations have expanded rapidly. Youth represent a particularly promising demographic for digital healthcare, for whom a key priority is access to sexual and reproductive health (SRH) services. Recent studies suggest that technology-based SRH services are perceived as confidential and private by youth. Still, among young people large-scale studies of population-based uptake remain sparce. However, in the general population digital solutions have been observed to be disproportionally accessed and adopted by more advantaged groups in the general population. Furthermore, comparisons of uptake across different digital modalities remain understudied, and it is unclear whether some might be more equitably accessed across sociodemographic groups than others. In this research project, we leverage Sweden’s unique national registries and health data to examine the dynamics of digital SRH service use among youth. The doctoral project focuses on youth clinics offering free-of-charge sexual and reproductive health services for youth 12-22 in Stockholm, Sweden. Whereas the first article focused on comparing uptake of in-person and digital services across sociodemographic groups (sex, age, migrant background and socioeconomic status), a forthcoming study will examine the uptake among neurotypical and neurodiverse youth (autism spectra and ADHD ).

2) Endometriosis is a common gynecological condition that can lead to chronic pain and infertility. Approximately 1/10 of all women of reproductive age are believed to be affected but underdiagnosis is common. Despite how common and costly the disease is, there is still no complete cure, and we know relatively little about how it develops. Women with endometriosis also have an increased risk of experiencing mental health issues. The most commonly observed comorbidity between endometriosis and psychiatric disorders is depression and anxiety disorders. It has previously largely been seen as a consequence of the chronic pain many endometriosis patients experience as well as the psychological toll of having a chronic disease. There have, however, been several studies, including one from our group, that have shown an increased incidence of other psychiatric disorders, such as bipolar disorder, ADHD , and personality disorders, where the link to pain is much less clear. In our project we want to examine other possible causes for the comorbidity, such as genetics and family environment, that could explain the high prevalence of mental disorders in endometriosis sufferers. To do this we utilize data from large national registers as well as genetic data to try to elucidate exactly how endometriosis and psychiatric disorders are linked.

• Speaker: 1) Marika Rostvall 2) Lovisa Hellsten. Both speakers are from the Karolinska Institutet
• Wednesday 16 April 2025, 11:30-13:00
• Venue: https://us02web.zoom.us/j/87076030035?pwd=XUpJuh8jiR0mae1AhkV79qbg8MtlSM.1.
• Series: ARClub Talks; organiser: Simon Braschi.

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Title to be confirmed

Abstract not available

• Speaker: Prof. Nikos Nikiforakis (Cambridge)
• Thursday 08 May 2025, 14:00-15:30
• Venue: Seminar Room 2, RDC.
• Series: Theory of Condensed Matter; organiser: Bo Peng.

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Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5EE00632E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Luis Huerta Hernandez, Luis Lanzetta, Anna M. Kotowska, Ilhan Yavuz, Nikhil Kalasariya, Badri Vishal, Martí Gibert-Roca, Matthew Piggott, David J Scurr, Stefaan De Wolf, Martin Stolterfoht, Derya Baran
Mixed ionic-electronic conduction is a prevalent phenomenon in metal halide perovskites, having a critical impact in multiple optoelectronic applications. In Sn-based halide perovskites, their higher hole density ([p]) owing to...
The content of this RSS Feed (c) The Royal Society of Chemistry

Centimeter-sized porous single-crystalline MoN monoliths with unsaturated Mo–N coordination structures are fabricated through solid-state phase transformation. The porous single-crystalline MoN integrates the structural features, suitable hydrogen adsorption energy, high electronic conductivity and intrinsic catalytic activity, demonstrating low Tafel slopes, minimal charge transfer resistances and long-term stability across all-pH conditions, significantly surpassing traditional Pt/C electrodes.

Abstract

Platinum is widely used in the important components in most electrochemical energy conversion systems while as a noble metal it faces the inevitable challenge of limited reserves. Herein, porous single–crystalline (PSC) molybdenum nitride (MoN) monoliths are reported at the centimeter scale that surpass platinum for all–pH hydrogen evolution. Free–standing PSC MoN electrode with the pore size of ≈6 nm and porosity of ≈72% present both noble–metal–like electronic structure and unsaturated Mo─N coordination structures at surface, contributing to remarkably high intrinsic electrocatalytic activity. The unprecedented overpotentials of as low as 13 and 11 mV are presented at the geometrical current density of 10 mA cm−2 for hydrogen evolution in H2SO4 (pH 0) and KOH (pH 14) media, respectively, which is dramatically superior to commercial Pt electrodes. As a result of the structural stability, the outstanding long–term durability for all pH hydrogen evolution is demonstrated without visible degradation in a continuous operation for 300 h.

This review presents a strategic vision for integrating micro- and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on usage scenarios.

Abstract

Medical micro- and nano-bots (MMBs and MNBs) have attracted a lot of attention owing to their precise motion for accessing difficult-to-reach areas in the body. These emerging tools offer the promise of non-invasive diagnostics and therapeutics for a wide range of ailments. Here, it is highlighted how MMBs and MNBs can revolutionize infection management. The latest applications of MMBs and MNBs are explored for infection prevention, including their use as accurate, minimally invasive surgeons and diagnosis, where they function as sensitive and rapid biosensors or carriers for contrast agents for real-time imaging of infected tissue. Further, the applications are outlined in treatment serving as anti-biofilm agents and smart carriers for antibiotics and anti-infective biologics. The current challenges in designing MMBs and MNBs are highlighted for overcoming immune barriers, moving to deep infected tissue, and swimming in low Reynolds numbers and discuss mitigating strategies. Finally, as a future perspective, the potential advantages of multi-drive propulsion, bioinspired, and artificial-intelligence-trained MMBs and MNBs are discussed, with a special focus on challenges and opportunities for their commercialization.

Soft chemical intercalation of the van der Waals magnetic semiconductor CrSBr induces a quasi-1D charge density wave (CDW) phase. The combination of this CDW with ferromagnetism from a spin-polarized band generates an unusual coupling of the charge and spin modulations in the intercalated material.

Abstract

In materials with 1D electronic bands, electron–electron interactions can produce intriguing quantum phenomena, including spin-charge separation and charge density waves (CDW). Most of these systems, however, are non-magnetic, motivating a search for anisotropic materials where the coupling of charge and spin may affect emergent quantum states. Here, chemical intercalation of the van der Waals magnetic semiconductor CrSBr yields Li0.17(2)(tetrahydrofuran)0.26(3)CrSBr, which possesses an electronically driven quasi-1D CDW with an onset temperature above room temperature. Concurrently, electron doping increases the magnetic ordering temperature from 132 to 200 K and switches its interlayer magnetic coupling from antiferromagnetic to ferromagnetic. The spin-polarized nature of the anisotropic bands that give rise to this CDW enforces an intrinsic coupling of charge and spin. The coexistence and interplay of ferromagnetism and charge modulation in this exfoliatable material provide a promising platform for studying tunable quantum phenomena across a range of temperatures and thicknesses.

Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5EE00412H, PaperFeng Jiang, Yun-Fei Du, Jia-Xin Guo, Nai-Lu Shen, Zi-Xian Chen, Mei Geng, Dongsheng Ren, Bo-Quan Li, Xue-Qiang Zhang, Tao Wang, Yuan Ma, Yiren Zhong, Jiarui He, Zhi Zhu, Faxing Wang, Jia-Qi Huang, Xin-Bing Cheng, Yuping Wu
The high-activity lithium metal anode limits the practical application of lithium-sulfur batteries in terms of both electrochemical performance and thermal safety. Solid electrolyte interphase (SEI) as a physical barrier between...
The content of this RSS Feed (c) The Royal Society of Chemistry

Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5EE00500K, PaperQiang Wu, Yuanke Wu, Hui Yan, Wei Zhong, Mingsheng Qin, Haolin Zhu, Shijie Cheng, Jia Xie
Sulfurized polyacrylonitrile (SPAN) is one of the most promising cathodes for high-energy-density lithium‒sulfur batteries since its distinctive organic skeleton and covalent sulfur storage mechanism effectively prevent polysulfide dissolution and mitigate...
The content of this RSS Feed (c) The Royal Society of Chemistry

Nature Energy, Published online: 11 April 2025; doi:10.1038/s41560-025-01753-5

An analysis of European carbon management shows that CO2 and H2 networks can complement each other. Transporting CO2 and H2 from low-cost regions with high availability to areas that process the two molecules into clean fuels or sequester CO2 could reduce total energy system costs by up to 5.3%.

Nature Energy, Published online: 11 April 2025; doi:10.1038/s41560-025-01752-6

This study on European carbon management shows how H2 and CO2 networks influence whether CO2 is transported to renewable hubs and sequestration sites or H2 is delivered to industrial sites for producing clean fuels from captured CO2.

Nature Nanotechnology, Published online: 11 April 2025; doi:10.1038/s41565-025-01882-8

By controlling the contribution of secondary nucleation in the self-assembly of chiral photoswitch molecules using light, it is possible to preferentially generate metastable aggregates, thereby reversing the supramolecular chirality.

Nature Nanotechnology, Published online: 11 April 2025; doi:10.1038/s41565-025-01906-3

In battery research, the areas of the electrodes and cell dimensions affect the energy storage performance. Here the authors discuss the factors that influence the reliability of electrochemical measurements and battery performance in lithium-ion cells with different electrode areas.

Nature Materials, Published online: 11 April 2025; doi:10.1038/s41563-025-02203-z

The formation of dislocations upon slip–slide events in organic crystals has been revealed by advanced electron microscopy and data-mining techniques.

Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5EE00071H, PaperSolomon T. Oyakhire, Sang Cheol Kim, Wenbo Zhang, Sanzeeda Baig Shuchi, Yi Cui, Stacey Bent
Current guidelines for electrolyte engineering in lithium metal batteries are based on design metrics such as lithium morphology, electrolyte transport properties, solid electrolyte interphase (SEI) characteristics, and lithium-electrolyte reactivity. In...
The content of this RSS Feed (c) The Royal Society of Chemistry

Energy Environ. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D4EE04820B, Review ArticleBoligarla Vinay, Yosef Nikodimos, Tripti Agnihotri, Shadab Ali Ahmed, Teklay Mezgebe Hagos, Rehbar Hasan, Elango Balaji Tamilarasan, Wei-Nien Su, Bing Joe Hwang
Electrolytes play a pivotal role in battery technologies, influencing performance and safety. However, electrolytes containing fluorine present adverse environmental risks due to their high greenhouse gas emissions and caution of...
The content of this RSS Feed (c) The Royal Society of Chemistry

Title to be confirmed

Abstract not available

• Speaker: Mikael Rechtsman, Penn State
• Friday 09 May 2025, 14:00-15:00
• Venue: Seminar Room 3, RDC.
• Series: Theory of Condensed Matter; organiser: Gaurav.

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Title to be confirmed

Abstract not available

• Speaker: Prof. Nikos Nikiforakis (Cambridge)
• Thursday 08 May 2025, 14:00-15:30
• Venue: Seminar Room 3, RDC.
• Series: Theory of Condensed Matter; organiser: Bo Peng.

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High-performance 721 nm-excitable solid upconversion porous aromatic frameworks (UC PAFs) was constructed and applied to a broad-range oxygen sensing and efficient heterogeneous photoredox catalysis. Moreover, homogeneous triple exciton energy is recognized to facilitate exciton diffusion, resulting in a high upconversion quantum yield (1.5% with an upper limit of 50%).

Abstract

The development of long-wavelength excitable solid upconversion materials and the regulation of exciton behavior is important for solar energy harvesting, photocatalysis, and other emerging applications. However, the approaches for regulating exciton diffusion are very limited, resulting in extremely poor photonic upconversion performance in solid-state. Here, the annihilation unit is integrated into porous aromatic frameworks (PAFs) and loaded with photosensitizer to construct efficient 721 nm-excitable solid upconversion material (upconversion quantum yield up to 1.5%, upper limit 50%). Most importantly, we found that the steric hindrance of annihilator units breaks the π-conjugation between the annihilation unit and the PAFs framework to form the homogeneous triplet exciton energy, which is conducive to the exciton diffusion. After increasing the exciton diffusion constant from 2.0 × 10−6 to 1.34 × 10−5 cm2 s−1, the upconversion quantum yield is increased ≈ 50-fold. Further, this solid upconversion material is utilized to demonstrate, for the first time, a broad-range oxygen sensing and 721 nm-driven heterogeneous and recyclable photoredox catalysis. These findings provide an important approach for regulating the behavior of triplet exciton in disorder solid materials to gain better upconversion performance, which will advance practical applications of organic photon upconversion in energy, chemistry, and photonics.